| EvanderAttacking midfielder |  FC Cincinnati | 🇧🇷Brazil | 28 | 25 | 24 | 7.3 | 73▲12.6%↩ | 39▼11.4%↩ |
| L. MessiCentre-forward |  Inter Miami | 🇦🇷Argentina | 39 | 35 | 23 | 1.2 | 100▲62.3% | 15▲49% |
| A. DreyerWinger |  San Diego | 🇩🇰Denmark | 28 | 23 | 17 | 7.7 | 75▲265.7%↩ | 41▼13.3%↩ |
| Jordi AlbaFull-back | Inter Miami | 🇪🇸Spain | 37 | 6 | 14 | 1.1 | 20▲31.6% | 14▼14.4% |
| P. ZinckernagelWinger |  Chicago Fire | 🇩🇰Denmark | 31 | 15 | 13 | 3.6 | 64▲270.9%↩ | 26±0% |
| D. YedlinFull-back | FC Cincinnati | 🇺🇸USA | 33 | 0 | 12 | 2 | 19▼17.5% | 18▼21% |
| L. SuárezCentre-forward | Inter Miami | 🇺🇾Uruguay | 39 | 10 | 11 | 0.9 | 50▼20.9% | 12▲3.4% |
| Pep BielWinger |  Charlotte | 🇪🇸Spain | 29 | 10 | 11 | 5.2 | 51▲310.4% | 30▼5.6% |
| S. BerhalterDefensive midfielder |  Vancouver Whitecaps | 🇺🇸USA | 25 | 4 | 10 | 15.2 | 59▲109.6% | 49▲13.5% |
| M. MoralezAttacking midfielder |  New York City FC | 🇦🇷Argentina | 39 | 3 | 9 | 1 | 32▲117.2% | 13▲109.4% |
| Carles GilCentral midfielder |  New England Revolution | 🇪🇸Spain | 33 | 10 | 9 | 2.3 | 56▲62.3% | 21▼7.8% |
| H. LozanoWinger | San Diego | 🇲🇽Mexico | 31 | 11 | 9 | 3.4 | 46▲227.9%↩ | 24▼39%↩ |
| A. GutmanFull-back | Chicago Fire | 🇺🇸USA | 29 | 3 | 9 | 4.6 | 27▲289.9% | 33▲15.2% |
| M. OjedaCentre-forward |  Orlando City SC | 🇦🇷Argentina | 27 | 16 | 9 | 12.7 | 63▲90% | 41▼9.5% |
| J. PereyraCentral midfielder |  Minnesota United FC | 🇦🇷Argentina | 27 | 7 | 9 | 12.9 | 56▲102.9%↩ | 41▼19.8%↩ |
| J. McGlynnAttacking midfielder |  Houston Dynamo | 🇺🇸USA | 23 | 6 | 9 | 14.9 | 48▲68.7%↩ | 48▲2.1%↩ |
| M. ReusAttacking midfielder |  Los Angeles Galaxy | 🇩🇪Germany | 37 | 5 | 8 | 0.7 | 37▲332.6% | 9▲15% |
| Sergio BusquetsCentral midfielder | Inter Miami | 🇪🇸Spain | 38 | 0 | 8 | 1.1 | 44▲19.3% | 14▼14.6% |
| E. ForsbergAttacking midfielder |  New York Red Bulls | 🇸🇪Sweden | 34 | 11 | 8 | 1.7 | 51▲50.7% | 19±0% |
| J. TverskovCentral midfielder | San Diego | 🇩🇰Denmark | 33 | 2 | 8 | 2.3 | 50▲82.9%↩ | 21▲10.5%↩ |
| A. RusnákAttacking midfielder |  Seattle Sounders | 🇸🇰Slovakia | 32 | 12 | 8 | 2.8 | 51▲9.7% | 23▼20.1% |
| C. EspinozaCentral midfielder |  San Jose Earthquakes | 🇦🇷Argentina | 31 | 4 | 8 | 3.6 | 48▲29.9% | 26▼24.1% |
| H. MukhtarCentre-forward |  Nashville SC | 🇩🇪Germany | 31 | 17 | 8 | 3.9 | 57▲25.7% | 28▼13.5% |
| D. BouangaCentre-forward |  Los Angeles FC | 🇬🇦Gabon | 31 | 26 | 8 | 4.1 | 78▲19.8% | 29▼13.9% |
| O. ValakariCentral midfielder | San Diego | 🇫🇮Finland | 26 | 5 | 8 | 14 | 47▲221.9%↩ | 45▲30.5%↩ |
| O. WolffWinger |  Austin | 🇺🇸USA | 21 | 7 | 8 | 11.5 | 41▲100.5% | 50▲15.6% |
| A. NajarFull-back | Nashville SC | 🇭🇳Honduras | 33 | 2 | 7 | 2.1 | 34▲85.8%↩ | 19▼4.5%↩ |
| M. DelgadoCentral midfielder | Los Angeles FC | 🇺🇸USA | 31 | 3 | 7 | 3.6 | 53▲40.4%↩ | 26▼15.7%↩ |
| D. JonesFull-back | San Jose Earthquakes | 🇺🇸USA | 29 | 1 | 7 | 2.8 | 13▼0.8%↩ | 27▼16.4%↩ |
| D. MihailovićAttacking midfielder |  Colorado Rapids | 🇺🇸USA | 27 | 13 | 7 | 12.8 | 52▲5% | 41▼11.6% |
| Q. SullivanAttacking midfielder |  Philadelphia Union | 🇺🇸USA | 22 | 2 | 7 | 8.9 | 30▼18.3% | 46▼3.8% |
| AntonyAttacking midfielder |  Portland Timbers | 🇧🇷Brazil | 24 | 7 | 7 | 13 | 42▲42.2% | 48▲5.1% |
| E. AtuestaCentral midfielder | Orlando City SC | 🇨🇴Colombia | 29 | 0 | 6 | 5.3 | 36▲1.1%↩ | 31▼14%↩ |
| Manu GarcíaAttacking midfielder |  Sporting Kansas City | 🇪🇸Spain | 28 | 2 | 6 | 4.8 | 26▲15.8%↩ | 31▼11.9%↩ |
| M. Haile-SelassieAttacking midfielder | Chicago Fire | 🇨🇭Switzerland | 27 | 2 | 6 | 6.1 | 19▼37.1% | 33▼18.5% |
| M. IloskiCentre-forward | Philadelphia Union | 🇺🇸USA | 27 | 13 | 6 | 11 | 40▲510.8%↩ | 35±0% |
| P. MusaCentre-forward |  FC Dallas | 🇭🇷Croatia | 28 | 19 | 6 | 6.8 | 64▲21.6% | 36▼14.6% |
| L. EngelWinger | FC Cincinnati | 🇩🇰Denmark | 27 | 0 | 6 | 7.1 | 15▲252.4%↩ | 38▼28.5%↩ |
| P. RothrockAttacking midfielder | Seattle Sounders | 🇺🇸USA | 27 | 4 | 6 | 8.9 | 29▲43.7% | 38▼4.5% |
| H. WolfAttacking midfielder | New York City FC | 🇦🇹Austria | 27 | 11 | 6 | 12.3 | 44▲38.5% | 39▼13.2% |
| P. DelgadoWinger | FC Dallas | 🇪🇨Ecuador | 22 | 1 | 6 | 7.6 | 20▼15.9% | 43▲0.5% |
| J. FerreiraAttacking midfielder | Seattle Sounders | 🇺🇸USA | 25 | 4 | 6 | 9 | 29▲25.5%↩ | 46▲8.8%↩ |
| David Pereira da CostaAttacking midfielder | Portland Timbers | 🇵🇹Portugal | 25 | 4 | 6 | 9.2 | 30▲1866.7%↩ | 46▼28.2%↩ |
| M. ArfstenDefensive midfielder |  Columbus Crew | 🇺🇸USA | 25 | 5 | 6 | 14.7 | 51▲91.8% | 47▲0.6% |
| L. MurielCentre-forward | Orlando City SC | 🇨🇴Colombia | 35 | 9 | 5 | 1.4 | 39▲57.6% | 15▲2.7% |
| D. LovitzFull-back | Nashville SC | 🇺🇸USA | 34 | 2 | 5 | 1.6 | 33▲29.7% | 17▼11.5% |
| W. ZahaAttacking midfielder | Charlotte | 🇨🇮Côte d'Ivoire | 33 | 10 | 5 | 2.2 | 43 | 21▼14.5%↩ |
| S. LobzhanidzeWinger |  Atlanta United FC | 🇬🇪Georgia | 31 | 0 | 5 | 2.3 | 16▼53.3% | 22▼28.9% |
| D. MusovskiCentre-forward | Seattle Sounders | 🇺🇸USA | 30 | 16 | 5 | 4 | 47▲719.3% | 26±0% |
| J. BambaWinger | Chicago Fire | 🇨🇮Côte d'Ivoire | 30 | 6 | 5 | 4.4 | 32▲620%↩ | 28▼44.2%↩ |
| D. GazdagAttacking midfielder | Columbus Crew | 🇭🇺Hungary | 30 | 6 | 5 | 4.5 | 35▼36.1%↩ | 29▼14.5%↩ |
| D. ChambostDefensive midfielder | Columbus Crew | 🇫🇷France | 28 | 2 | 5 | 6.5 | 38▲310.9% | 35±0% |
| P. BuchaDefensive midfielder | FC Cincinnati | 🇨🇿Czechia | 28 | 4 | 5 | 6.6 | 36▼10.9% | 35▼20.5% |
| S. MorenoWinger | Portland Timbers | 🇨🇴Colombia | 26 | 4 | 5 | 7.6 | 25▼30% | 39▼16.8% |
| A. OjedaCentre-forward | New York City FC | 🇦🇷Argentina | 22 | 0 | 5 | 7.3 | 13▲26.5% | 41▼1.7% |
| J. FernándezWinger | New York City FC | 🇦🇷Argentina | 22 | 3 | 5 | 7.5 | 20▲94.1% | 42▲1% |
| O. ValenciaDefensive midfielder | New York Red Bulls | 🇵🇦Panama | 22 | 0 | 5 | 7.6 | 26 | 43▲19.2% |
| D. MartínezCentre-forward | Los Angeles FC | 🇻🇪Venezuela | 20 | 3 | 5 | 7.2 | 20▲61.1% | 45▲6.1% |
| J. NelsonAttacking midfielder | Vancouver Whitecaps | 🇨🇦Canada | 23 | 2 | 5 | 8.5 | 22▲217.6%↩ | 45▲11%↩ |
| N. RomeroCentre-back | Minnesota United FC | 🇦🇷Argentina | 22 | 0 | 5 | 8.1 | 26▼49.7%↩ | 46▼23.7%↩ |
| Marco PasalicCentral midfielder | Orlando City SC | 🇭🇷Croatia | 25 | 12 | 5 | 14.9 | 57 | 48▼27.3%↩ |
| E. Choupo-MotingCentre-forward | New York Red Bulls | 🇨🇲Cameroon | 37 | 17 | 4 | 1.1 | 59▲317%↩ | 14▼13.9%↩ |
| A. PellegrinoWinger | San Diego | 🇳🇴Norway | 36 | 7 | 4 | 1.4 | 42▲46.6%↩ | 15▲13.2%↩ |
| R. HollingsheadFull-back | Los Angeles FC | 🇺🇸USA | 35 | 2 | 4 | 1.5 | 34▼17% | 16▼7.2% |
| R. De PaulCentral midfielder | Inter Miami | 🇦🇷Argentina | 32 | 1 | 4 | 2 | 19▼51.2%↩ | 16▼67.8%↩ |
| A. WestwoodDefensive midfielder | Charlotte | 🏴England | 36 | 1 | 4 | 1.7 | 34▲1.2% | 18▼1.6% |
| E. ThommyAttacking midfielder | Sporting Kansas City | 🇩🇪Germany | 31 | 4 | 4 | 2.6 | 22▼35.5% | 19▼39.5% |
| Sergio SantosWinger | FC Cincinnati | 🇧🇷Brazil | 31 | 3 | 4 | 2.6 | 18▲30.9% | 19▼24.4% |
| M. YamaneFull-back | Los Angeles Galaxy | 🇯🇵Japan | 32 | 1 | 4 | 2.4 | 20▼35.2% | 19▼31.2% |
| R. LodCentral midfielder | Minnesota United FC | 🇫🇮Finland | 33 | 6 | 4 | 2.2 | 46±0% | 20▼21.1% |
| M. AlmirónCentral midfielder | Atlanta United FC | 🇵🇾Paraguay | 32 | 6 | 4 | 3 | 46▲5033.3%↩ | 24▼28.8%↩ |
| André FrancoAttacking midfielder | Chicago Fire | 🇵🇹Portugal | 28 | 0 | 4 | 2.9 | 9▲32.4%↩ | 26▼47%↩ |
| A. MuylCentral midfielder | Nashville SC | 🇺🇸USA | 30 | 1 | 4 | 4.1 | 29▼18.6% | 26▼19.2% |
| J. DeanFull-back | Chicago Fire | 🇺🇸USA | 29 | 1 | 4 | 3.5 | 20▲56.6% | 28▼0.7% |
| M. HartelAttacking midfielder |  St. Louis City | 🇩🇪Germany | 30 | 9 | 4 | 4.6 | 39▲104.8% | 30▲3.5% |
| L. LappalainenWinger | Columbus Crew | 🇫🇮Finland | 27 | 1 | 4 | 5.6 | 11 | 30▼10.5%↩ |
| D. RossiCentre-forward | Columbus Crew | 🇺🇾Uruguay | 28 | 16 | 4 | 6.9 | 54▲41.5% | 37▼15% |
| I. AnguloCentral midfielder | Orlando City SC | 🇨🇴Colombia | 27 | 0 | 4 | 9.3 | 30▼34.2% | 37▼24% |
| G. DorseyFull-back | Houston Dynamo | 🇺🇸USA | 27 | 2 | 4 | 10.3 | 33▼6% | 38▼12.3% |
| L. EnnaliCentral midfielder | Houston Dynamo | 🇩🇪Germany | 24 | 1 | 4 | 10 | 32▲1433.3% | 41▲5.4% |
| P. de la VegaAttacking midfielder | Seattle Sounders | 🇦🇷Argentina | 25 | 4 | 4 | 7.8 | 23▲234.8% | 41▲11% |
| L. PetrassoFull-back |  CF Montreal | 🇨🇦Canada | 26 | 2 | 4 | 7.8 | 15 | 42▲22.9%↩ |
| C. ClarkWinger | CF Montreal | 🇺🇸USA | 23 | 0 | 4 | 7.9 | 13▲78.7%↩ | 42▲6.9%↩ |
| T. SegoviaAttacking midfielder | Inter Miami | 🇻🇪Venezuela | 23 | 9 | 4 | 10.1 | 32▲76.1%↩ | 45▼24.7%↩ |
| J. HaakCentre-back | New York City FC | 🇺🇸USA | 24 | 2 | 4 | 13.1 | 42▲323.2% | 46▲17.6% |
| T. MüllerAttacking midfielder | Vancouver Whitecaps | 🇩🇪Germany | 36 | 8 | 3 | 1 | 25▲37%↩ | 11▼47.5%↩ |
| Son Heung-MinCentre-forward | Los Angeles FC | 🇰🇷Korea Republic | 34 | 12 | 3 | 1.1 | 34▼27.6%↩ | 11▼69.5%↩ |
| C. BentekeCentre-forward |  DC United | 🇧🇪Belgium | 35 | 9 | 3 | 1.4 | 40▼44% | 15▼22.4% |
| J. GresselCentral midfielder | Minnesota United FC | 🇺🇸USA | 32 | 1 | 3 | 1.9 | 18▼40.4%↩ | 16▼42.4%↩ |
| A. LassiterWinger | Portland Timbers | 🇨🇷Costa Rica | 31 | 0 | 3 | 1.3 | 8▼57.9%↩ | 16▼42.9%↩ |
| F. MoraCentre-forward | Portland Timbers | 🇨🇱Chile | 33 | 7 | 3 | 2.3 | 28▼37.1% | 19▼28.2% |
| RamiroFull-back | FC Dallas | 🇧🇷Brazil | 33 | 0 | 3 | 2.1 | 29▲33.6%↩ | 19▼38.8%↩ |
| D. RíosCentre-forward | Vancouver Whitecaps | 🇲🇽Mexico | 31 | 4 | 3 | 3 | 22▲0.5%↩ | 22▼15.6%↩ |
| C. BairdCentre-forward | San Diego | 🇺🇸USA | 30 | 0 | 3 | 2.1 | 9▼36.2%↩ | 22▼23.4%↩ |
| B. BronicoAttacking midfielder | Charlotte | 🇺🇸USA | 31 | 2 | 3 | 2.6 | 19▼27.5% | 23▼19.3% |
| M. DeslerCentral midfielder | Austin | 🇩🇰Denmark | 31 | 1 | 3 | 3.2 | 37▲527.1% | 23▲7.5% |
| R. KentWinger | Seattle Sounders | 🏴England | 29 | 0 | 3 | 2.4 | 10 | 24▼31.9%↩ |
| M. UzuniCentre-forward | Austin | 🇦🇱Albania | 31 | 6 | 3 | 3.4 | 31▼16.1%↩ | 24▼40.4%↩ |
| D. EtienneAttacking midfielder |  Toronto FC | 🇭🇹Haiti | 29 | 0 | 3 | 2.5 | 10▼26.5% | 25▼24.7% |
| C. RoldanDefensive midfielder | Seattle Sounders | 🇺🇸USA | 31 | 1 | 3 | 3.5 | 41▲26.2% | 25▼19.7% |
