| K. Kossa-RienziFull-back |  Seattle Sounders | 🇺🇸USA | 24 | 3 | 2 | 8 | 19▲9300% | 43▲24.3% |
| F. SurmanCentre-back |  Portland Timbers | 🇳🇿New Zealand | 22 | 0 | 0 | 8.4 | 28▲7000% | 46▲27.8% |
| Belal HalbouniCentre-back |  Vancouver Whitecaps | 🇸🇾Syria | 26 | 0 | 0 | 6.4 | 12▲6000% | 34▲2.1% |
| I. ParenteCentral midfielder |  Los Angeles Galaxy | 🇺🇸USA | 26 | 0 | 1 | 6 | 12▲5850% | 32▼4.2% |
| C. RindovCentre-back | Los Angeles Galaxy | 🇺🇸USA | 24 | 0 | 0 | 6.3 | 6▲5700%↩ | 34▼4%↩ |
| M. DugganFull-back |  Minnesota United FC | 🇩🇪Germany | 25 | 0 | 2 | 7.7 | 16▲5300% | 41▲20.6% |
| M. AlmirónCentral midfielder |  Atlanta United FC | 🇵🇾Paraguay | 32 | 6 | 4 | 2.9 | 46▲4955.6%↩ | 23▼31.2%↩ |
| B. ServaniaDefensive midfielder |  DC United | 🇺🇸USA | 27 | 0 | 2 | 8 | 26▲4200%↩ | 34▲8.3%↩ |
| J. RickettsCentral midfielder |  San Jose Earthquakes | 🇺🇸USA | 24 | 1 | 2 | 7.1 | 17▲4100% | 38▲9.8% |
| É. OcampoFull-back | Vancouver Whitecaps | 🇨🇴Colombia | 22 | 2 | 0 | 11 | 37▲3610% | 47▲29% |
| M. JoynerCentral midfielder |  St. Louis City | 🇺🇸USA | 19 | 1 | 0 | 5.7 | 7▲3550% | 38▲4.7% |
| P. RuizCentral midfielder |  Real Salt Lake | 🇦🇷Argentina | 27 | 0 | 1 | 5.7 | 13▲3025% | 31▼8.1% |
| N. NorrisFull-back |  FC Dallas | 🇺🇸USA | 21 | 0 | 1 | 6.8 | 6▲2950% | 40▲9.5% |
| H. DiopCentre-back |  San Diego | 🇸🇳Senegal | 24 | 0 | 0 | 6.8 | 3▲2900%↩ | 36▲3.7%↩ |
| D. BugajFull-back |  CF Montreal | 🇵🇱Poland | 22 | 0 | 2 | 7.4 | 14▲2700% | 42▲14.6% |
| David Pereira da CostaCentral midfielder | Portland Timbers | 🇵🇹Portugal | 25 | 4 | 6 | 10.2 | 33▲2086.7%↩ | 46▼28.2%↩ |
| D. SchneggDefensive midfielder | DC United | 🇦🇹Austria | 27 | 0 | 1 | 9.4 | 30▲1906.7% | 37▲10.8% |
| Cavan SullivanCentral midfielder |  Philadelphia Union | 🇺🇸USA | 16 | 0 | 0 | 4.6 | 2▲1900% | 38▲7.1% |
| Giuseppe BovalinaFull-back | Vancouver Whitecaps | 🇦🇺Australia | 21 | 0 | 2 | 7 | 4▲1650% | 41▲12.8% |
| J. NgandoAttacking midfielder | Vancouver Whitecaps | 🇨🇲Cameroon | 26 | 2 | 3 | 7.1 | 14▲1600% | 38▲11.4% |
| H. WingoFull-back |  Toronto FC | 🇺🇸USA | 30 | 0 | 0 | 1.6 | 3▲1550% | 18▼22.9% |
| Raul GustavoFull-back |  New York City FC | 🇧🇷Brazil | 27 | 0 | 1 | 5.7 | 11▲1442.9%↩ | 30▼42.3%↩ |
| L. BrennanCentral midfielder | Atlanta United FC | 🇺🇸USA | 21 | 0 | 1 | 6.6 | 5▲1433.3% | 39▲8% |
| V. LoturiCentral midfielder | CF Montreal | 🇨🇦Canada | 25 | 2 | 0 | 9.4 | 30▲1410%↩ | 42▲12.6%↩ |
| T. HabrouneCentral midfielder |  Columbus Crew | 🇺🇸USA | 20 | 1 | 1 | 6.7 | 13▲1355.6% | 42▲9.1% |
| E. MoralesCentre-back | CF Montreal | 🇧🇴Bolivia | 22 | 0 | 0 | 6.9 | 11▲1300%↩ | 39▲7.2%↩ |
| N. CaliskanDefensive midfielder | Real Salt Lake | 🇩🇪Germany | 25 | 1 | 1 | 8.2 | 26▲1278.9% | 40▲13.9% |
| A. RickGoalkeeper | Philadelphia Union | 🇺🇸USA | 20 | 0 | 0 | 6.6 | 21▲1212.5% | 42▲9.2% |
| D. PadelfordFull-back | St. Louis City | 🇺🇸USA | 23 | 0 | 1 | 6.7 | 7▲1200%↩ | 36▼4.8%↩ |
| L. StefanovicCentre-back | Toronto FC | 🇨🇦Canada | 19 | 0 | 0 | 5.8 | 6▲1160% | 39▲11.8% |
| B. CeballosCentre-back |  New England Revolution | 🇨🇴Colombia | 25 | 1 | 0 | 12 | 38▲966.7%↩ | 43▲18.5%↩ |
| L. NdenbeCentre-back |  Sporting Kansas City | 🇧🇪Belgium | 26 | 1 | 0 | 6.6 | 16▲900% | 35▲4.1% |
| L. EngelFull-back |  FC Cincinnati | 🇩🇰Denmark | 27 | 0 | 4 | 11.9 | 38▲809.5%↩ | 38▼28.1%↩ |
| D. Jean-JacquesDefensive midfielder | Philadelphia Union | 🇭🇹Haiti | 26 | 3 | 2 | 11.5 | 37▲720% | 39▲14.2% |
| D. MusovskiCentre-forward | Seattle Sounders | 🇺🇸USA | 30 | 16 | 5 | 4 | 47▲719.3% | 26±0% |
| R. CannonCentre-back |  Colorado Rapids | 🇺🇸USA | 28 | 0 | 0 | 5.5 | 29▲648.7% | 32±0% |
| J. BambaAttacking midfielder |  Chicago Fire | 🇨🇮Côte d'Ivoire | 30 | 6 | 5 | 4.4 | 32▲620%↩ | 28▼43.4%↩ |
| D. SealyWinger | CF Montreal | 🇺🇸USA | 23 | 9 | 1 | 10.8 | 35▲580.4%↩ | 46▲18%↩ |
| T. ÁngelCentre-forward | San Diego | 🇨🇴Colombia | 23 | 3 | 2 | 7.8 | 13▲557.9%↩ | 41▲1.7%↩ |
| L. EnnaliWinger |  Houston Dynamo | 🇩🇪Germany | 24 | 1 | 4 | 6.9 | 14▲552.4% | 37▼5.4% |
| DanielGoalkeeper | San Jose Earthquakes | 🇧🇷Brazil | 32 | 0 | 0 | 1.5 | 6▲544.4% | 21▲1% |
| J. BondGoalkeeper | Houston Dynamo | 🏴England | 33 | 0 | 0 | 1.8 | 23▲513.5%↩ | 16▼33.3%↩ |
| M. IloskiCentre-forward | Philadelphia Union | 🇺🇸USA | 27 | 13 | 6 | 11 | 40▲510.8%↩ | 35±0% |
| Rafael CabralGoalkeeper | Real Salt Lake | 🇧🇷Brazil | 36 | 0 | 0 | 1.1 | 12▲490%↩ | 18▲58.4%↩ |
| Felipe AndradeCentre-back | Houston Dynamo | 🇧🇷Brazil | 24 | 4 | 1 | 8.8 | 28▲475.5%↩ | 41▼27%↩ |
| A. MarkanichCentre-back | Minnesota United FC | 🇺🇸USA | 26 | 10 | 1 | 11 | 35▲425.4%↩ | 41▲3.6%↩ |
| O. SvatokCentre-back |  Austin | 🇺🇦Ukraine | 31 | 1 | 0 | 3.3 | 26▲415.7% | 23▲9.4% |
| O. VerhoevenCentre-back | San Diego | 🇺🇸USA | 20 | 0 | 0 | 6.7 | 11▲395.7%↩ | 42▲10.6%↩ |
| N. HagglundCentre-back | FC Cincinnati | 🇺🇸USA | 33 | 1 | 0 | 1.6 | 17▲394.3% | 15▼3.2% |
| T. D'AvillaDefensive midfielder | Chicago Fire | 🇨🇮Côte d'Ivoire | 23 | 2 | 1 | 7.7 | 22▲391.1%↩ | 41▼17.6%↩ |
| B. RainesCentral midfielder | Houston Dynamo | 🇺🇸USA | 21 | 0 | 0 | 6.9 | 12▲376% | 41▲8.2% |
| M. DominguezDefensive midfielder | Toronto FC | 🇨🇭Switzerland | 30 | 0 | 1 | 2.8 | 18▲373.7%↩ | 22▼43.8%↩ |
| N. OrdazCentre-forward |  Los Angeles FC | 🇸🇻El Salvador | 22 | 6 | 3 | 7.9 | 24▲361.5% | 44▲10.7% |
| P. JuddCentre-forward | San Jose Earthquakes | 🇺🇸USA | 27 | 6 | 2 | 7 | 22▲355.1% | 33▼7.8% |
| A. YusufDefensive midfielder | New England Revolution | 🇳🇬Nigeria | 26 | 2 | 1 | 11.5 | 37▲353.1% | 42▲18.6% |
| R. PrisoCentral midfielder | Vancouver Whitecaps | 🇨🇦Canada | 24 | 1 | 2 | 7.8 | 21▲328.6% | 42▲8% |
| A. BlakeGoalkeeper | Philadelphia Union | 🇯🇲Jamaica | 35 | 0 | 0 | 1.3 | 29▲320.3% | 13▲15.5% |
| E. Choupo-MotingCentre-forward |  New York Red Bulls | 🇨🇲Cameroon | 37 | 17 | 4 | 1.1 | 59▲317%↩ | 14▼13.9%↩ |
| J. HaakDefensive midfielder | New York City FC | 🇺🇸USA | 24 | 2 | 4 | 12.7 | 41▲312.1% | 46▲17.4% |
| T. HadebeFull-back | FC Cincinnati | 🇿🇼Zimbabwe | 30 | 0 | 1 | 3.3 | 25▲311.7% | 21▼21.6% |
| D. ChambostCentral midfielder | Columbus Crew | 🇫🇷France | 28 | 2 | 5 | 6.5 | 38▲310.9% | 35±0% |
| J. LöffelsendFull-back | San Diego | 🇩🇪Germany | 28 | 0 | 2 | 3.1 | 15▲305.6%↩ | 28▼10%↩ |
| P. MillerFull-back | New England Revolution | 🇺🇸USA | 18 | 2 | 2 | 6.4 | 26▲304.7% | 46▲15.2% |
| P. OrtízCentre-back | Houston Dynamo | 🇨🇴Colombia | 26 | 1 | 0 | 6.4 | 18▲302.2%↩ | 34▼8.6%↩ |
| P. PomykalDefensive midfielder | FC Dallas | 🇺🇸USA | 26 | 0 | 0 | 5.5 | 0▲300% | 29▼11.2% |
| M. SuleymanovWinger | Sporting Kansas City | 🇷🇺Russia | 26 | 2 | 3 | 6.8 | 18▲300%↩ | 36▲6.2%↩ |
| A. MoralesDefensive midfielder | St. Louis City | 🇺🇸USA | 36 | 0 | 2 | 0.9 | 16▲297.5%↩ | 10▲23.8%↩ |
| PeglowCentral midfielder | DC United | 🇧🇷Brazil | 24 | 3 | 3 | 9.9 | 32▲292.6%↩ | 43▲24.9%↩ |
| A. GutmanFull-back | Chicago Fire | 🇺🇸USA | 29 | 3 | 9 | 4.6 | 27▲289.9% | 33▲15.2% |
| B. ByeCentre-back | New England Revolution | 🇺🇸USA | 30 | 0 | 0 | 2.4 | 16▲282.9% | 21▼20.8% |
| M. ReusAttacking midfielder | Los Angeles Galaxy | 🇩🇪Germany | 37 | 5 | 8 | 0.6 | 32▲268.6% | 8▲1.2% |
| Pep BielWinger |  Charlotte | 🇪🇸Spain | 29 | 10 | 11 | 5 | 46▲266.4% | 29▼8.7% |
| A. DreyerCentre-forward | San Diego | 🇩🇰Denmark | 28 | 23 | 17 | 7.7 | 75▲265.7%↩ | 41▼13.3%↩ |
| P. ZinckernagelWinger | Chicago Fire | 🇩🇰Denmark | 31 | 15 | 13 | 3.6 | 62▲261%↩ | 25▼0.8%↩ |
| O. BukariCentral midfielder | Austin | 🇬🇭Ghana | 27 | 3 | 3 | 9.5 | 31▲255.8% | 39▲5.4% |
| O. HolmDefensive midfielder | Los Angeles FC | 🇳🇴Norway | 23 | 0 | 0 | 6.6 | 1▲250%↩ | 36▼13%↩ |
| T. BeasonCentre-back | New England Revolution | 🇺🇸USA | 29 | 0 | 1 | 4.7 | 32▲246.2%↩ | 28▼14.6%↩ |
| M. FreeseGoalkeeper | New York City FC | 🇺🇸USA | 27 | 0 | 0 | 8.3 | 27▲235.4% | 38▼16.3% |
| P. YazbekCentral midfielder |  Nashville SC | 🇦🇺Australia | 24 | 1 | 0 | 7.9 | 23▲231.9%↩ | 42▲6.3%↩ |
| M. DeslerFull-back | Austin | 🇩🇰Denmark | 31 | 1 | 3 | 2.7 | 19▲220.3% | 20▼5.6% |
| C. ClarkCentral midfielder | CF Montreal | 🇺🇸USA | 23 | 0 | 4 | 7.9 | 24▲218.7%↩ | 42▲7.4%↩ |
| S. RogersCentre-back | Chicago Fire | 🇺🇸USA | 27 | 0 | 0 | 6.1 | 15▲217.4%↩ | 33▲14.8%↩ |
| P. SisniegaGoalkeeper | San Diego | 🇲🇽Mexico | 31 | 0 | 0 | 1.4 | 9▲213.3%↩ | 17▼30%↩ |
| M. TurnerGoalkeeper | New England Revolution | 🇺🇸USA | 32 | 0 | 0 | 1.1 | 8▲207.4%↩ | 14▼69.7%↩ |
| D. YapiCentre-forward | Colorado Rapids | 🇺🇸USA | 21 | 8 | 2 | 8.1 | 29▲207.4% | 44▲4.5% |
| H. LozanoWinger | San Diego | 🇲🇽Mexico | 31 | 11 | 9 | 3.3 | 42▲202.9%↩ | 24▼40.6%↩ |
| M. MoralezCentral midfielder | New York City FC | 🇦🇷Argentina | 39 | 3 | 9 | 1 | 44▲201.4% | 13▲109.4% |
| A. IvačičGoalkeeper | New England Revolution | 🇸🇮Slovenia | 32 | 0 | 0 | 2.3 | 19▲198.4% | 20▼19% |
| P. de la VegaWinger | Seattle Sounders | 🇦🇷Argentina | 25 | 4 | 4 | 7.5 | 20▲189.9% | 40▲8% |
| D. MunieCentre-back | San Jose Earthquakes | 🇺🇸USA | 26 | 2 | 1 | 6.9 | 17▲189.5% | 37▼1.9% |
| M. PinedaFull-back | Chicago Fire | 🇺🇸USA | 28 | 0 | 2 | 3.4 | 14▲187.8% | 30▼6% |
| B. KamungoCentral midfielder | FC Dallas | 🇹🇿Tanzania | 24 | 2 | 1 | 7.5 | 21▲183.8% | 40▼1.7% |
| S. DoumbiaFull-back | Charlotte | 🇨🇮Côte d'Ivoire | 29 | 0 | 1 | 2.4 | 12▲183.3%↩ | 23▼35.3%↩ |
| J. PulskampGoalkeeper | Sporting Kansas City | 🇺🇸USA | 25 | 0 | 2 | 8 | 4▲168.7% | 43▲16.1% |
| T. ReamCentre-back | Charlotte | 🇺🇸USA | 38 | 0 | 0 | 0.9 | 35▲160.7% | 11▲13.4% |
| J. HopkinsCentral midfielder | DC United | 🇺🇸USA | 22 | 3 | 0 | 7.1 | 15▲160.7% | 40▲2.6% |
| C. AntleyFull-back | DC United | 🇺🇸USA | 31 | 1 | 1 | 1.6 | 12▲157.8% | 19▼13.8% |
| J. HornCentral midfielder | St. Louis City | 🇩🇪Germany | 29 | 0 | 1 | 2.3 | 8▲154.8% | 22▼24.1% |
| J. NelsonWinger | Vancouver Whitecaps | 🇨🇦Canada | 23 | 2 | 5 | 8 | 17▲152.9%↩ | 43▲5.4%↩ |
| C. AwaziemCentre-back | Colorado Rapids | 🇳🇬Nigeria | 29 | 0 | 1 | 2.7 | 16▲149.2%↩ | 26▼18.4%↩ |
