| N. ToloCentre-back |  Seattle Sounders | 🇨🇲Cameroon | 29 | 0 | 1 | 5.2 | 40▲66.4% | 31▲5.8% |
| M. UzuniCentre-forward |  Austin | 🇦🇱Albania | 31 | 6 | 0 | 3.4 | 39▲39.9% | 24▲1.3% |
| D. MihailovićCentre-forward |  Toronto FC | 🇺🇸USA | 27 | 2 | 3 | 11.4 | 39±0% | 33▼11.9%↩ |
| S. HeftiFull-back |  DC United | 🇨🇭Switzerland | 28 | 1 | 2 | 6.7 | 39▲110.2%↩ | 36▼28.9%↩ |
| A. RoldanCentre-back | Seattle Sounders | 🇸🇻El Salvador | 30 | 0 | 0 | 3.7 | 39▲46.8% | 22▼12.9% |
| D. AyalaCentral midfielder |  Inter Miami | 🇦🇷Argentina | 24 | 0 | 0 | 6.7 | 39±0% | 35▼19.2%↩ |
| J. McGlynnAttacking midfielder |  Houston Dynamo | 🇺🇸USA | 23 | 2 | 5 | 11.3 | 39▼2.7% | 48▲4.8% |
| B. OjedaCentral midfielder |  Orlando City SC | 🇵🇾Paraguay | 26 | 1 | 2 | 12.1 | 39▲50.8%↩ | 43▲13%↩ |
| Mateo SilvettiWinger | Inter Miami | 🇦🇷Argentina | 20 | 3 | 4 | 11.9 | 39▲211.2%↩ | 45▼4.4%↩ |
| D. LunaAttacking midfielder |  Real Salt Lake | 🇺🇸USA | 22 | 5 | 3 | 12.8 | 39▲6.3% | 46▼2.1% |
| R. DonkorCentral midfielder |  New York Red Bulls | 🇲🇱Mali | 21 | 1 | 4 | 11.2 | 39▲141.6% | 48▲17.3% |
| João KlaussCentre-forward |  Los Angeles Galaxy | 🇧🇷Brazil | 29 | 5 | 0 | 4.8 | 39±0% | 25▼16%↩ |
| R. RobertsCentre-back |  San Jose Earthquakes | 🇺🇸USA | 22 | 2 | 0 | 9.4 | 39▲360.7% | 49▲30.9% |
| L. FarringtonWinger |  FC Dallas | 🇺🇸USA | 24 | 6 | 2 | 11.2 | 39▲62.4% | 45▲5.6% |
| J. AlonsoCentre-back |  Atlanta United FC | 🇵🇾Paraguay | 33 | 0 | 0 | 0.9 | 38±0% | 10▼63.3%↩ |
| B. CeballosCentre-back |  CF Montreal | 🇨🇴Colombia | 25 | 2 | 0 | 6.1 | 38±0% | 33▼23.5%↩ |
| David Pereira da CostaAttacking midfielder |  Portland Timbers | 🇵🇹Portugal | 25 | 3 | 6 | 13.7 | 38▲16.2% | 43▼6.1% |
| P. RothrockCentral midfielder | Seattle Sounders | 🇺🇸USA | 27 | 5 | 1 | 11.5 | 38▲36.3% | 37▼2.1% |
| M. LongstaffCentral midfielder | CF Montreal | 🏴England | 26 | 2 | 3 | 11.9 | 38▲109.4%↩ | 43▲17.9%↩ |
| C. RoldanAttacking midfielder | Seattle Sounders | 🇺🇸USA | 31 | 3 | 1 | 3.4 | 38▼5% | 21▼14.6% |
| Alonso CoelloDefensive midfielder | Toronto FC | 🇪🇸Spain | 26 | 0 | 3 | 12.5 | 38▲33.1% | 40▲4.4% |
| N. TriantisCentral midfielder |  Minnesota United FC | 🇦🇺Australia | 23 | 1 | 1 | 11.3 | 38▲447.8% | 42▲2.2% |
| C. HolseWinger |  St. Louis City | 🇩🇰Denmark | 27 | 0 | 0 | 5.1 | 38±0% | 26▼39.1%↩ |
| W. MadrigalWinger |  Nashville SC | 🇨🇷Costa Rica | 22 | 5 | 2 | 11.8 | 38 | 45 |
| M. FofanaCentre-back |  New England Revolution | 🇲🇱Mali | 28 | 1 | 0 | 6.4 | 38▼15% | 35▲4.2% |
| O. BlorianCentre-back |  Sporting Kansas City | 🇮🇱Israel | 26 | 0 | 0 | 5.7 | 38±0% | 39±0% |
| I. Toklomati GiornoCentre-forward |  Charlotte | 🇮🇱Israel | 22 | 6 | 2 | 11.9 | 38▼4.8% | 48▲2.1% |
| J. TverskovDefensive midfielder |  San Diego | 🇩🇰Denmark | 33 | 0 | 1 | 2 | 37▼25.6% | 15▼27.6% |
| D. SallóiAttacking midfielder | Toronto FC | 🇭🇺Hungary | 30 | 5 | 4 | 4.7 | 37▲15.6%↩ | 30▲20.6%↩ |
| D. FagundezCentral midfielder | New England Revolution | 🇺🇾Uruguay | 31 | 0 | 0 | 1.3 | 37±0% | 15▼34.8%↩ |
| T. HabrouneDefensive midfielder |  Columbus Crew | 🇺🇸USA | 20 | 1 | 2 | 9.8 | 37▲182.4% | 46▲10.8% |
| Justin EllisWinger | Orlando City SC | 🇺🇸USA | 19 | 1 | 4 | 8.2 | 37 | 45▲25% |
| T. BlackmonCentre-back |  Vancouver Whitecaps | 🇺🇸USA | 30 | 1 | 0 | 4.7 | 37▲29.1% | 29▲15% |
| N. CaliskanDefensive midfielder | Real Salt Lake | 🇩🇪Germany | 26 | 0 | 3 | 12.4 | 37▲40.1% | 46▲23.6% |
| A. NajarFull-back | Nashville SC | 🇭🇳Honduras | 33 | 2 | 3 | 1.9 | 37▲10.6% | 16▼15.9% |
| E. ForsbergAttacking midfielder | New York Red Bulls | 🇸🇪Sweden | 34 | 3 | 4 | 1.6 | 37▼27.5% | 17▼7.7% |
| D. LasGoalkeeper | Austin | 🇺🇸USA | 24 | 0 | 0 | 6 | 37▲6.4%↩ | 39▲18.8%↩ |
| O. BoudaCentral midfielder | San Jose Earthquakes | 🇧🇫Burkina Faso | 26 | 5 | 1 | 13.3 | 37▲149% | 43▲19.6% |
| K. RowlesCentre-back | DC United | 🇦🇺Australia | 28 | 2 | 0 | 6.6 | 37▲26.3% | 34▲2.1% |
| B. TraoréCentre-forward |  New York City FC | 🇨🇮Côte d'Ivoire | 23 | 1 | 0 | 7.5 | 37▲12%↩ | 37▼22.3%↩ |
| J. BadwalCentral midfielder | Vancouver Whitecaps | 🇨🇦Canada | 20 | 1 | 2 | 9.7 | 37▲157% | 49▲14.7% |
| L. MunteanuCentre-forward | DC United | 🇷🇴Romania | 24 | 5 | 1 | 11 | 36▲161.9%↩ | 43▲33.5%↩ |
| E. AtuestaCentral midfielder | Orlando City SC | 🇨🇴Colombia | 29 | 0 | 3 | 4.8 | 36▲9.7% | 26▼12.1% |
| J. RosalesCentral midfielder | Austin | 🇭🇳Honduras | 25 | 1 | 2 | 11.6 | 36▲96.7%↩ | 41±0% |
| N. HarrielFull-back |  Philadelphia Union | 🇺🇸USA | 25 | 1 | 2 | 10.4 | 36▼24.8% | 45▲7.7% |
| J. OsorioCentral midfielder | Toronto FC | 🇨🇦Canada | 34 | 0 | 3 | 1.7 | 36▲84% | 17▲25.7% |
| Bryan Josías Ramírez LeónDefensive midfielder |  FC Cincinnati | 🇪🇨Ecuador | 26 | 0 | 2 | 11.1 | 36 | 40 |
| M. Haile-SelassieWinger |  Chicago Fire | 🇨🇭Switzerland | 27 | 4 | 4 | 11.9 | 36▲94.5% | 38▲17.8% |
| V. LoturiCentral midfielder | CF Montreal | 🇨🇦Canada | 25 | 1 | 1 | 10.9 | 36▲17.5% | 44▲3.8% |
| M. PeltolaDefensive midfielder | DC United | 🇫🇮Finland | 24 | 1 | 0 | 11.1 | 36▲127.6% | 45▲12.9% |
| A. GutmanFull-back | Chicago Fire | 🇺🇸USA | 29 | 1 | 3 | 5.3 | 35▲31.6% | 29▼9.8% |
| D. MartínezWinger |  Los Angeles FC | 🇻🇪Venezuela | 20 | 6 | 0 | 8.9 | 35▲78.8% | 47▲4.4% |
| J. DavisDefensive midfielder | Sporting Kansas City | 🇺🇸USA | 24 | 0 | 2 | 11 | 35▲165.2% | 43▲11% |
| A. MățanWinger | St. Louis City | 🇷🇴Romania | 27 | 0 | 1 | 5.3 | 35±0% | 30▼10.2%↩ |
| D. VazquezCentral midfielder | San Diego | 🇺🇸USA | 20 | 3 | 0 | 9.2 | 35▲3370% | 43▲9.8% |
| E. SabbiWinger | Vancouver Whitecaps | 🇺🇸USA | 28 | 3 | 3 | 6.5 | 34▲14.3% | 32▼5.3% |
| G. ValenzuelaCentral midfielder | FC Cincinnati | 🇺🇸USA | 21 | 1 | 3 | 10.8 | 34▲119.2% | 44▲5.5% |
| A. WestwoodCentral midfielder | Charlotte | 🏴England | 36 | 2 | 3 | 1.6 | 34▲0.9% | 18▼1.1% |
| Loïc WilliamsCentre-back |  Colorado Rapids | 🇪🇸Spain | 24 | 1 | 0 | 7.2 | 34±0% | 38▼40.1%↩ |
| D. PolvaraCentre-back | St. Louis City | 🇺🇸USA | 26 | 1 | 0 | 10 | 34▲153.7%↩ | 42▲16.1%↩ |
| A. GriezmannCentre-forward | Orlando City SC | 🇫🇷France | 35 | 3 | 2 | 1.2 | 34±0% | 8▼63.2%↩ |
| T. TillmanCentral midfielder | Los Angeles FC | 🇩🇪Germany | 27 | 1 | 2 | 10.1 | 33▲35.8% | 37▼2.1% |
| E. KarićCentre-back | Sporting Kansas City | 🇦🇹Austria | 29 | 0 | 0 | 2.5 | 33▲2.2%↩ | 21▼36.7%↩ |
| J. ElliottFull-back | Chicago Fire | 🏴England | 31 | 0 | 1 | 3.4 | 33▲32.9% | 27▲4.7% |
| Beau LerouxAttacking midfielder | San Jose Earthquakes | 🇺🇸USA | 23 | 3 | 3 | 9.1 | 33▼25.1% | 50▲7.1% |
| Leonardo BarrosoCentre-back | Chicago Fire | 🇵🇹Portugal | 21 | 0 | 0 | 8.5 | 33▲219.4% | 42▲5.3% |
| K. Kossa-RienziCentral midfielder | Seattle Sounders | 🇺🇸USA | 24 | 3 | 0 | 12.1 | 33▲75% | 43▼0.9% |
| J. PereyraWinger | Minnesota United FC | 🇦🇷Argentina | 27 | 3 | 7 | 12.2 | 33▼20.1% | 37▼8.3% |
| M. DugganCentre-back | Minnesota United FC | 🇩🇪Germany | 25 | 1 | 0 | 10 | 33▲101.2% | 45▲8.5% |
| P. YazbekAttacking midfielder | Nashville SC | 🇦🇺Australia | 24 | 1 | 3 | 9.6 | 33▲41.9% | 41▼1.7% |
| C. BassettAttacking midfielder | Portland Timbers | 🇺🇸USA | 25 | 3 | 3 | 11.6 | 33▲10.5%↩ | 44▲0.7%↩ |
| J. HopkinsCentral midfielder | DC United | 🇺🇸USA | 22 | 2 | 1 | 9.5 | 33▲122.6% | 46▲16.3% |
| K. NonoAttacking midfielder | DC United | 🇯🇵Japan | 24 | 0 | 1 | 6.7 | 32±0% | 37▼30.1%↩ |
| M. BoguszWinger | Houston Dynamo | 🇵🇱Poland | 25 | 4 | 1 | 9.4 | 32▲337.8%↩ | 49▲7.5%↩ |
| A. MarkanichFull-back | Minnesota United FC | 🇺🇸USA | 26 | 5 | 2 | 11.3 | 32▼9.4% | 42▲4.2% |
| J. DíazCentre-back | Minnesota United FC | 🇨🇴Colombia | 25 | 0 | 1 | 9.7 | 32▲27.1% | 43▼1.8% |
| C. CowellWinger | New York Red Bulls | 🇺🇸USA | 22 | 2 | 5 | 9.2 | 32▲289%↩ | 46▼4.9%↩ |
| J. WatermanCentre-back | Chicago Fire | 🇨🇦Canada | 30 | 1 | 0 | 4.1 | 32▲76.7%↩ | 23▼7.2%↩ |
| S. SpieringsDefensive midfielder | Real Salt Lake | 🇳🇱Netherlands | 30 | 1 | 1 | 3.7 | 32▲78.5%↩ | 24▲13.7%↩ |
| O. LarrazCentral midfielder | Vancouver Whitecaps | 🇺🇸USA | 24 | 0 | 2 | 9 | 32±0% | 41▼5.3%↩ |
| T. BeasonCentre-back | New England Revolution | 🇺🇸USA | 29 | 0 | 0 | 2 | 32±0% | 20▼28.4% |
| W. SandsCentre-back | New England Revolution | 🇺🇸USA | 26 | 1 | 0 | 9 | 32▲258% | 42▲27.3% |
| KaickCentral midfielder | FC Dallas | 🇧🇷Brazil | 20 | 1 | 1 | 8 | 32▲29.1% | 47▲9.3% |
| R. LodAttacking midfielder | Chicago Fire | 🇫🇮Finland | 33 | 4 | 1 | 1.9 | 31▼30.4%↩ | 17▼14.4%↩ |
| F. TorresAttacking midfielder | Austin | 🇺🇾Uruguay | 26 | 2 | 5 | 10.4 | 31▲9.8%↩ | 40▼37.8%↩ |
| J. SanabriaCentral midfielder | Real Salt Lake | 🇺🇾Uruguay | 26 | 1 | 4 | 12.9 | 31▲86.9%↩ | 41▼7.5%↩ |
| R. HoldingCentre-back | Colorado Rapids | 🏴England | 30 | 0 | 0 | 4 | 31▲404.8% | 25▲36.9% |
| J. TravisFull-back | Colorado Rapids | 🇺🇸USA | 22 | 0 | 1 | 9.3 | 31▲595.6% | 43▲13% |
| A. CvetkovićCentral midfielder | Vancouver Whitecaps | 🇷🇸Serbia | 21 | 3 | 3 | 9.3 | 31 | 43 |
| J. ValienteAttacking midfielder | FC Dallas | 🇺🇾Uruguay | 25 | 1 | 6 | 9.2 | 31 | 43 |
| B. RainesCentral midfielder | New England Revolution | 🇺🇸USA | 21 | 1 | 0 | 8.7 | 31▲160.5%↩ | 47▲14.4%↩ |
| MicaelCentre-back | Inter Miami | 🇧🇷Brazil | 26 | 1 | 0 | 10.3 | 31▲27.7%↩ | 40▼30.7%↩ |
| P. MillerCentre-forward | New England Revolution | 🇺🇸USA | 18 | 4 | 3 | 8.6 | 31▲19.3% | 49▲7.9% |
| C. BradyGoalkeeper | Chicago Fire | 🇺🇸USA | 22 | 0 | 0 | 8.5 | 31▲305.3% | 48▲6.2% |
| Gabriel PiraniCentral midfielder | San Diego | 🇧🇷Brazil | 24 | 0 | 0 | 7.1 | 31±0% | 37▼16%↩ |
| H. DotsonDefensive midfielder | Seattle Sounders | 🇺🇸USA | 29 | 1 | 0 | 4.9 | 31▲350%↩ | 26▲16.3%↩ |
| C. dos SantosGoalkeeper | San Diego | 🇺🇸USA | 26 | 0 | 0 | 6.4 | 31±0% | 36▼14.8% |
| J. HaakDefensive midfielder | Los Angeles Galaxy | 🇺🇸USA | 24 | 0 | 1 | 9.4 | 31▼25.2%↩ | 42▼8.1%↩ |
| Y. BrightDefensive midfielder | Inter Miami | 🇮🇹Italy | 24 | 0 | 0 | 9.4 | 30▲46.2% | 43▲11.3% |
| C. RamirezCentre-forward | Austin | 🇺🇸USA | 35 | 5 | 1 | 1.1 | 30▲74.6%↩ | 12▲20.8%↩ |
