| D. MalenCentre-forward | AS Roma | 🇳🇱Netherlands | 27 | 14 | 2 | 77.6 | 87▲600.8%↩ | 75▲11.4%↩ |
| J. ButezGoalkeeper | Como | 🇫🇷France | 31 | 0 | 1 | 22.9 | 84▲1479.2% | 49▲5.6% |
| Lautaro MartínezCentre-forward | Inter | 🇦🇷Argentina | 28 | 17 | 6 | 41.7 | 81▲45.6% | 67▼14% |
| F. DimarcoCentral midfielder | Inter | 🇮🇹Italy | 28 | 7 | 16 | 43.6 | 80▲114.1% | 70▼9% |
| Y. SommerGoalkeeper | Inter | 🇨🇭Switzerland | 37 | 0 | 0 | 6.3 | 76▲29.3% | 24▼22.5% |
| Jacobo Ramón NaverosCentre-back | Como | 🇪🇸Spain | 21 | 2 | 0 | 71 | 76▲1369.2%↩ | 89▲14.7%↩ |
| M. SvilarGoalkeeper | AS Roma | 🇷🇸Serbia | 26 | 0 | 0 | 77.6 | 75▲24.5% | 81▼7.9% |
| G. ManciniFull-back | AS Roma | 🇮🇹Italy | 30 | 4 | 2 | 28.4 | 73▲19.2% | 55▼15% |
| WesleyFull-back | AS Roma | 🇧🇷Brazil | 22 | 5 | 0 | 69.2 | 71▲77.4%↩ | 91▲23%↩ |
| M. ThuramCentre-forward | Inter | 🇫🇷France | 29 | 13 | 6 | 40.6 | 70▲14.2% | 66▼17.4% |
| E. NdickaCentre-back | AS Roma | 🇨🇮Côte d'Ivoire | 26 | 3 | 0 | 70.9 | 69▲17.4% | 79▼9.8% |
| M. AkanjiCentre-back | Inter | 🇨🇭Switzerland | 31 | 2 | 0 | 21.3 | 68▲132.9%↩ | 46▼16.4%↩ |
| R. HøjlundCentre-forward | Napoli | 🇩🇰Denmark | 23 | 12 | 5 | 68.3 | 66▲227.7%↩ | 93▲10.9%↩ |
| S. McTominayDefensive midfielder | Napoli | 🏴Scotland | 29 | 10 | 3 | 34.9 | 66▲19.9% | 61▼19.4% |
| A. RabiotCentral midfielder | AC Milan | 🇫🇷France | 31 | 6 | 4 | 24.2 | 65▲27.9%↩ | 52▼11.5%↩ |
| K. DavisCentre-forward | Udinese | 🏴England | 28 | 10 | 4 | 38.4 | 62▲404.1% | 64▲3.9% |
| N. PazAttacking midfielder | Como | 🇦🇷Argentina | 21 | 12 | 6 | 56.7 | 61▲36.1% | 95▲4.5% |
| BremerCentre-back | Juventus | 🇧🇷Brazil | 29 | 4 | 3 | 34.3 | 60▲261.7% | 61▲12.2% |
| Mario GilaCentre-back | Lazio | 🇪🇸Spain | 25 | 0 | 0 | 61.6 | 60▲79.3% | 81▼2.2% |
| HermosoFull-back | AS Roma | 🇪🇸Spain | 31 | 3 | 2 | 20.7 | 59▲1102%↩ | 45▲14.4%↩ |
| K. ThorstvedtCentral midfielder | Sassuolo | 🇳🇴Norway | 27 | 4 | 4 | 60.3 | 58▲77% | 72▲10% |
| A. BastoniFull-back | Inter | 🇮🇹Italy | 27 | 1 | 4 | 59.9 | 58▲21.8% | 71▼14.5% |
| P. KaluluFull-back | Juventus | 🇫🇷France | 26 | 2 | 4 | 59.3 | 58▼17.7% | 82▲2.1% |
| Saúl CocoFull-back | Torino | 🇬🇶Equatorial Guinea | 27 | 1 | 1 | 59.1 | 57▲40.4% | 69▼11.3% |
| L. KellyFull-back | Juventus | 🏴England | 27 | 1 | 1 | 59.1 | 57▲195.4% | 71▲3.1% |
| O. SoletFull-back | Udinese | 🇫🇷France | 26 | 3 | 1 | 58.6 | 57▲160.6% | 75±0% |
| I. ProvedelGoalkeeper | Lazio | 🇮🇹Italy | 32 | 0 | 0 | 17.8 | 57▲218.5% | 43▼10.6% |
| R. MandragoraCentral midfielder | Fiorentina | 🇮🇹Italy | 29 | 7 | 3 | 32.2 | 57▲55.3% | 57▼15% |
| F. TomoriFull-back | AC Milan | 🏴England | 28 | 0 | 2 | 35 | 57▲85% | 61▼6.1% |
| A. RomagnoliCentre-back | Lazio | 🇮🇹Italy | 31 | 0 | 0 | 20.9 | 56▲73.5% | 45▼16.9% |
| B. DjimsitiCentre-back | Atalanta | 🇦🇱Albania | 33 | 0 | 0 | 11.6 | 56▼4.1% | 32▼26.3% |
| T. DouvikasCentre-forward | Como | 🇬🇷Greece | 27 | 14 | 1 | 57.3 | 56▲308.1%↩ | 77▲2.8%↩ |
| W. McKennieDefensive midfielder | Juventus | 🇺🇸USA | 27 | 5 | 5 | 56.6 | 55▲50.5% | 75▼7.1% |
| G. Di LorenzoFull-back | Napoli | 🇮🇹Italy | 33 | 2 | 1 | 17.7 | 55▼27.5% | 43▼22.2% |
| N. BarellaCentral midfielder | Inter | 🇮🇹Italy | 29 | 3 | 8 | 31 | 55▲19% | 59▼18.5% |
| Rafael LeãoCentre-forward | AC Milan | 🇵🇹Portugal | 27 | 9 | 3 | 56.1 | 54▲13.1% | 70▼12.9% |
| S. PavlovićFull-back | AC Milan | 🇷🇸Serbia | 25 | 5 | 1 | 56.1 | 54▲64.4% | 84▲10% |
| A. MarušićFull-back | Lazio | 🇲🇪Montenegro | 33 | 1 | 2 | 12.4 | 54▲136.7% | 34▼17.3% |
| L. da CunhaDefensive midfielder | Como | 🇫🇷France | 25 | 6 | 4 | 55.9 | 54▲41.9% | 88▲10.8% |
| Álex ValleFull-back | Como | 🇪🇸Spain | 22 | 1 | 4 | 52.9 | 54▲429.4% | 85▲16.7% |
| K. YıldızAttacking midfielder | Juventus | 🇹🇷Türkiye | 21 | 10 | 6 | 52 | 54▲39.9% | 93▲2.8% |
| A. IsmajliCentre-back | Torino | 🇦🇱Albania | 29 | 0 | 1 | 30.6 | 54▲91.8%↩ | 55▼11.1%↩ |
| H. ÇalhanoğluAttacking midfielder | Inter | 🇹🇷Türkiye | 32 | 9 | 4 | 16.3 | 53▲53.6% | 40▼17.5% |
| G. ScalviniFull-back | Atalanta | 🇮🇹Italy | 22 | 3 | 1 | 52.2 | 53▲964% | 84▲18.5% |
| L. ValentiFull-back | Parma | 🇦🇷Argentina | 27 | 0 | 0 | 54.8 | 53▲305.3% | 65▼3.4% |
| A. SaelemaekersCentral midfielder | AC Milan | 🇧🇪Belgium | 27 | 3 | 3 | 54.7 | 53▲82.8%↩ | 70▼6.9%↩ |
| A. CircatiFull-back | Parma | 🇦🇺Australia | 22 | 1 | 0 | 50.8 | 52▲1133.3% | 84▲25.4% |
| M. KempfCentre-back | Como | 🇩🇪Germany | 31 | 4 | 1 | 19.9 | 52▲103.5% | 43▼18.8% |
| Danilo VeigaFull-back | Lecce | 🇵🇹Portugal | 23 | 0 | 1 | 53 | 51▲225.3%↩ | 80▲35.8%↩ |
| Amir RrahmaniCentre-back | Napoli | 🇽🇰Kosovo | 32 | 2 | 1 | 16.3 | 51▼28.2% | 40▼28.6% |
| Diego CarlosCentre-back | Como | 🇧🇷Brazil | 33 | 1 | 0 | 10.1 | 50▲530%↩ | 28▼14.4%↩ |
| G. SimeoneCentre-forward | Torino | 🇦🇷Argentina | 31 | 11 | 0 | 19.8 | 50▲641.2%↩ | 43▼1.6%↩ |
| A. BuongiornoFull-back | Napoli | 🇮🇹Italy | 27 | 0 | 1 | 52 | 50▼8.4% | 69▼10.3% |
| F. TerraccianoFull-back | Cremonese | 🇮🇹Italy | 23 | 3 | 0 | 52 | 50▲530%↩ | 81▲15%↩ |
| M. LocatelliDefensive midfielder | Juventus | 🇮🇹Italy | 28 | 1 | 2 | 31.1 | 50▲12.8% | 64▼15.3% |
| M. MaignanGoalkeeper | AC Milan | 🇫🇷France | 31 | 0 | 0 | 22.6 | 50▲14.4% | 49▼17.1% |
| C. PulišićCentre-forward | AC Milan | 🇺🇸USA | 27 | 8 | 4 | 51.1 | 50▼14.7% | 68▼19.7% |
| D. VlahovićCentre-forward | Juventus | 🇷🇸Serbia | 26 | 7 | 1 | 51.1 | 50▲5.5% | 72▼13.1% |
| M. GabbiaCentre-back | AC Milan | 🇮🇹Italy | 26 | 0 | 0 | 51.1 | 50▲59.2% | 77±0% |
| A. AttaDefensive midfielder | Udinese | 🇫🇷France | 23 | 5 | 3 | 53 | 50▲277.9% | 86▲18.1% |
| A. CambiasoDefensive midfielder | Juventus | 🇮🇹Italy | 26 | 3 | 4 | 50.8 | 49▲7.2% | 78▼5.5% |
| G. OrbanCentre-forward | Hellas Verona | 🇳🇬Nigeria | 24 | 7 | 2 | 50.8 | 49▲213.4%↩ | 79▲11.8%↩ |
| A. LaurientéWinger | Sassuolo | 🇫🇷France | 27 | 7 | 9 | 50.6 | 49▼2% | 69▲3.4% |
| M. Di GregorioGoalkeeper | Juventus | 🇮🇹Italy | 29 | 0 | 0 | 27.7 | 49▼27.6% | 55▼21.9% |
| A. PinamontiCentre-forward | Sassuolo | 🇮🇹Italy | 27 | 9 | 3 | 50.2 | 49▲2.3%↩ | 67▼15.5%↩ |
| N. KrstovićCentre-forward | Atalanta | 🇲🇪Montenegro | 26 | 10 | 5 | 50.2 | 49▼19.1%↩ | 73▼11.6%↩ |
| R. MalinovskyiDefensive midfielder | Genoa | 🇺🇦Ukraine | 33 | 6 | 3 | 11.3 | 48▲747.4% | 31▲14.7% |
| M. PerroneDefensive midfielder | Como | 🇦🇷Argentina | 23 | 3 | 4 | 54.4 | 48▲81.4% | 88▲9.2% |
| L. ModrićCentral midfielder | AC Milan | 🇭🇷Croatia | 40 | 2 | 3 | 6.1 | 47▲81.6%↩ | 24▲39.4%↩ |
| F. BonazzoliCentre-forward | Cremonese | 🇮🇹Italy | 29 | 10 | 1 | 26.7 | 47▲170.1% | 52▲9.9% |
| M. KonéDefensive midfielder | AS Roma | 🇫🇷France | 25 | 2 | 3 | 53.7 | 47▲41.7% | 87▲5.7% |
| M. KeanWinger | Fiorentina | 🇮🇹Italy | 26 | 8 | 1 | 47.4 | 46▼32.9% | 73▼15.6% |
| D. CataldiCentral midfielder | Lazio | 🇮🇹Italy | 32 | 3 | 3 | 20.4 | 46▲26.9%↩ | 44▼11.6%↩ |
| Y. BisseckFull-back | Inter | 🇩🇪Germany | 25 | 3 | 1 | 49.4 | 46▲39.1% | 80▼4% |
| S. EspositoCentre-forward | Cagliari | 🇮🇹Italy | 24 | 7 | 5 | 51.2 | 45▲23.6%↩ | 83▲4.8%↩ |
| K. ThuramDefensive midfielder | Juventus | 🇫🇷France | 25 | 3 | 3 | 52.6 | 45▼3.4% | 85▼3% |
| G. ScamaccaCentre-forward | Atalanta | 🇮🇹Italy | 27 | 10 | 1 | 46.2 | 45 | 64▲4.8% |
| Juan MirandaFull-back | Bologna | 🇪🇸Spain | 26 | 1 | 3 | 46.1 | 45▲44.2% | 74▼8.7% |
| V. Milinković-SavićGoalkeeper | Napoli | 🇷🇸Serbia | 29 | 0 | 1 | 25.3 | 45▲71.2%↩ | 56▼20%↩ |
| I. HienCentre-back | Atalanta | 🇸🇪Sweden | 27 | 1 | 0 | 45.9 | 45▼6.9% | 64▼17.6% |
| G. MaripánCentre-back | Torino | 🇨🇱Chile | 32 | 2 | 0 | 14 | 44▲26.4% | 34▼24.7% |
| I. SmolčićFull-back | Como | 🇭🇷Croatia | 25 | 0 | 1 | 45.6 | 44▲516.9% | 74▲10.5% |
| Tiago GabrielCentre-back | Lecce | 🇵🇹Portugal | 21 | 2 | 0 | 46.8 | 44▲205.6%↩ | 84▲50.8%↩ |
| J. VardyCentre-forward | Cremonese | 🏴England | 39 | 7 | 2 | 5.1 | 44▼8.8%↩ | 20▼17.6%↩ |
| M. de RoonDefensive midfielder | Atalanta | 🇳🇱Netherlands | 35 | 1 | 2 | 9.3 | 43▼26.8% | 30▼20.6% |
| A. ObertFull-back | Cagliari | 🇸🇰Slovakia | 23 | 0 | 3 | 50 | 43▲159.6% | 81▲15.1% |
| F. BaschirottoCentre-back | Cremonese | 🇮🇹Italy | 29 | 2 | 0 | 24.4 | 43▲31.2%↩ | 55▼19.6%↩ |
| D. BerardiCentre-forward | Sassuolo | 🇮🇹Italy | 32 | 8 | 4 | 14.1 | 43▼2.3% | 34▼14.5% |
| M. CarnesecchiGoalkeeper | Atalanta | 🇮🇹Italy | 26 | 0 | 0 | 48.2 | 43▼14.4% | 78▼9.5% |
| N. VlašićAttacking midfielder | Torino | 🇭🇷Croatia | 28 | 8 | 3 | 26.4 | 43▲34.4% | 64▼12.1% |
| Carlos AugustoFull-back | Inter | 🇧🇷Brazil | 27 | 1 | 1 | 43.9 | 43▲30.4% | 64▼19.9% |
| R. GagliardiniDefensive midfielder | Hellas Verona | 🇮🇹Italy | 32 | 1 | 0 | 14.3 | 42▲1909.5%↩ | 35▲16.8%↩ |
| M. SouléAttacking midfielder | AS Roma | 🇦🇷Argentina | 23 | 6 | 5 | 54.9 | 42▲3.2% | 89▲3.5% |
| Mateo PellegrinoWinger | Parma | 🇦🇷Argentina | 24 | 9 | 1 | 51.6 | 42▼23.2%↩ | 83▲34.1%↩ |
| M. AebischerCentral midfielder | Pisa | 🇨🇭Switzerland | 29 | 1 | 2 | 23.8 | 42▲565.1%↩ | 53▲0.6%↩ |
| T. MuharemovićCentre-back | Sassuolo | 🇧🇦Bosnia and Herzegovina | 23 | 2 | 2 | 51.2 | 42▲13.9% | 83▲23.4% |
| K. De BruyneAttacking midfielder | Napoli | 🇧🇪Belgium | 35 | 5 | 2 | 8.5 | 42▲24.1%↩ | 28▼7.7%↩ |
| J. LucumíCentre-back | Bologna | 🇨🇴Colombia | 28 | 1 | 0 | 25.8 | 42▲2.5% | 60▼17% |
| M. KeitaCentral midfielder | Parma | 🇧🇪Belgium | 24 | 1 | 1 | 49.5 | 42▲64.8% | 80▲8.4% |
| Adrián BernabéCentral midfielder | Parma | 🇪🇸Spain | 25 | 3 | 1 | 49.7 | 41▲102.9% | 80▲15.6% |