| Lautaro MartínezCentre-forward | Inter | 🇦🇷Argentina | 28 | 17 | 6 | 41.7 | 81▲45.6% | 67▼14% |
| D. MalenCentre-forward | AS Roma | 🇳🇱Netherlands | 27 | 14 | 2 | 77.6 | 87▲600.8%↩ | 75▲11.4%↩ |
| T. DouvikasCentre-forward | Como | 🇬🇷Greece | 27 | 14 | 1 | 57.3 | 56▲308.1%↩ | 77▲2.8%↩ |
| M. ThuramCentre-forward | Inter | 🇫🇷France | 29 | 13 | 6 | 40.6 | 70▲14.2% | 66▼17.4% |
| R. HøjlundCentre-forward | Napoli | 🇩🇰Denmark | 23 | 12 | 5 | 68.3 | 66▲227.7%↩ | 93▲10.9%↩ |
| N. PazAttacking midfielder | Como | 🇦🇷Argentina | 21 | 12 | 6 | 56.7 | 61▲36.1% | 95▲4.5% |
| G. SimeoneCentre-forward | Torino | 🇦🇷Argentina | 31 | 11 | 0 | 19.8 | 50▲641.2%↩ | 43▼1.6%↩ |
| F. BonazzoliCentre-forward | Cremonese | 🇮🇹Italy | 29 | 10 | 1 | 26.7 | 47▲170.1% | 52▲9.9% |
| R. OrsoliniWinger | Bologna | 🇮🇹Italy | 29 | 10 | 1 | 23 | 41▼25.5% | 53▼20.4% |
| S. McTominayDefensive midfielder | Napoli | 🏴Scotland | 29 | 10 | 3 | 34.9 | 66▲19.9% | 61▼19.4% |
| G. ScamaccaCentre-forward | Atalanta | 🇮🇹Italy | 27 | 10 | 1 | 46.2 | 45 | 64▲4.8% |
| K. DavisCentre-forward | Udinese | 🏴England | 28 | 10 | 4 | 38.4 | 62▲404.1% | 64▲3.9% |
| N. KrstovićCentre-forward | Atalanta | 🇲🇪Montenegro | 26 | 10 | 5 | 50.2 | 49▼19.1%↩ | 73▼11.6%↩ |
| K. YıldızAttacking midfielder | Juventus | 🇹🇷Türkiye | 21 | 10 | 6 | 52 | 54▲39.9% | 93▲2.8% |
| H. ÇalhanoğluAttacking midfielder | Inter | 🇹🇷Türkiye | 32 | 9 | 4 | 16.3 | 53▲53.6% | 40▼17.5% |
| A. PinamontiCentre-forward | Sassuolo | 🇮🇹Italy | 27 | 9 | 3 | 50.2 | 49▲2.3%↩ | 67▼15.5%↩ |
| Rafael LeãoCentre-forward | AC Milan | 🇵🇹Portugal | 27 | 9 | 3 | 56.1 | 54▲13.1% | 70▼12.9% |
| Mateo PellegrinoWinger | Parma | 🇦🇷Argentina | 24 | 9 | 1 | 51.6 | 42▼23.2%↩ | 83▲34.1%↩ |
| D. BerardiCentre-forward | Sassuolo | 🇮🇹Italy | 32 | 8 | 4 | 14.1 | 43▼2.3% | 34▼14.5% |
| N. VlašićAttacking midfielder | Torino | 🇭🇷Croatia | 28 | 8 | 3 | 26.4 | 43▲34.4% | 64▼12.1% |
| C. PulišićCentre-forward | AC Milan | 🇺🇸USA | 27 | 8 | 4 | 51.1 | 50▼14.7% | 68▼19.7% |
| M. KeanWinger | Fiorentina | 🇮🇹Italy | 26 | 8 | 1 | 47.4 | 46▼32.9% | 73▼15.6% |
| J. VardyCentre-forward | Cremonese | 🏴England | 39 | 7 | 2 | 5.1 | 44▼8.8%↩ | 20▼17.6%↩ |
| S. MoreoCentre-forward | Pisa | 🇮🇹Italy | 33 | 7 | 1 | 10.2 | 36▲1.4% | 28▼16.8% |
| C. NkunkuCentre-forward | AC Milan | 🇫🇷France | 28 | 7 | 3 | 21.7 | 35▲105.9%↩ | 57▼19.6%↩ |
| R. MandragoraCentral midfielder | Fiorentina | 🇮🇹Italy | 29 | 7 | 3 | 32.2 | 57▲55.3% | 57▼15% |
| A. LaurientéWinger | Sassuolo | 🇫🇷France | 27 | 7 | 9 | 50.6 | 49▼2% | 69▲3.4% |
| F. DimarcoCentral midfielder | Inter | 🇮🇹Italy | 28 | 7 | 16 | 43.6 | 80▲114.1% | 70▼9% |
| D. VlahovićCentre-forward | Juventus | 🇷🇸Serbia | 26 | 7 | 1 | 51.1 | 50▲5.5% | 72▼13.1% |
| L. ColomboCentre-forward | Genoa | 🇮🇹Italy | 24 | 7 | 1 | 47.9 | 33▼2.6%↩ | 77▼6.5%↩ |
| G. OrbanCentre-forward | Hellas Verona | 🇳🇬Nigeria | 24 | 7 | 2 | 50.8 | 49▲213.4%↩ | 79▲11.8%↩ |
| S. EspositoCentre-forward | Cagliari | 🇮🇹Italy | 24 | 7 | 5 | 51.2 | 45▲23.6%↩ | 83▲4.8%↩ |
| S. CastroCentre-forward | Bologna | 🇦🇷Argentina | 21 | 7 | 2 | 47.4 | 38▼15.6% | 85▼2.5% |
| F. EspositoCentre-forward | Inter | 🇮🇹Italy | 21 | 7 | 3 | 48 | 36▼38.4%↩ | 86▲12.5%↩ |
| R. MalinovskyiDefensive midfielder | Genoa | 🇺🇦Ukraine | 33 | 6 | 3 | 11.3 | 48▲747.4% | 31▲14.7% |
| P. ZielińskiCentral midfielder | Inter | 🇵🇱Poland | 32 | 6 | 3 | 15.7 | 41▲191.5% | 38▼5.9% |
| C. AdamsAttacking midfielder | Torino | 🏴Scotland | 30 | 6 | 2 | 16.1 | 31▼34.6% | 44▼28.1% |
| A. RabiotCentral midfielder | AC Milan | 🇫🇷France | 31 | 6 | 4 | 24.2 | 65▲27.9%↩ | 52▼11.5%↩ |
| J. DavidCentre-forward | Juventus | 🇨🇦Canada | 26 | 6 | 4 | 44.1 | 36▼48.5%↩ | 71▼18.5%↩ |
| C. CasadeiDefensive midfielder | Torino | 🇮🇹Italy | 23 | 6 | 0 | 48.9 | 37▲170.8% | 79▲10.5% |
| I. KonéCentral midfielder | Sassuolo | 🇨🇦Canada | 24 | 6 | 0 | 51.1 | 41▲495.7%↩ | 83▲25.9%↩ |
| M. BaturinaAttacking midfielder | Como | 🇭🇷Croatia | 23 | 6 | 3 | 51.3 | 31 | 83 |
| L. da CunhaDefensive midfielder | Como | 🇫🇷France | 25 | 6 | 4 | 55.9 | 54▲41.9% | 88▲10.8% |
| M. SouléAttacking midfielder | AS Roma | 🇦🇷Argentina | 23 | 6 | 5 | 54.9 | 42▲3.2% | 89▲3.5% |
| PedroWinger | Lazio | 🇪🇸Spain | 39 | 5 | 2 | 2.9 | 24▼33.1% | 11▼4.2% |
| K. De BruyneAttacking midfielder | Napoli | 🇧🇪Belgium | 35 | 5 | 2 | 8.5 | 42▲24.1%↩ | 28▼7.7%↩ |
| A. GuðmundssonWinger | Fiorentina | 🇮🇸Iceland | 29 | 5 | 4 | 19.4 | 34▲30.2% | 53▼13.9% |
| J. OdgaardCentre-forward | Bologna | 🇩🇰Denmark | 27 | 5 | 1 | 37.6 | 27▼12.4% | 61▼19.4% |
| G. BorrelliCentre-forward | Cagliari | 🇮🇹Italy | 26 | 5 | 1 | 40.8 | 31▲14.2%↩ | 66▲4.4%↩ |
| N. ZanioloWinger | Udinese | 🇮🇹Italy | 27 | 5 | 6 | 42.7 | 41▲97.6%↩ | 69▼4.8%↩ |
| VítinhaAttacking midfielder | Genoa | 🇵🇹Portugal | 26 | 5 | 1 | 43 | 27▲51.1% | 69▼4% |
| L. ØstigårdCentre-back | Genoa | 🇳🇴Norway | 26 | 5 | 1 | 45.3 | 37▲81.4%↩ | 73▲9.1%↩ |
| G. IsaksenWinger | Lazio | 🇩🇰Denmark | 25 | 5 | 1 | 45.5 | 25±0% | 74▼8.2% |
| L. BandaAttacking midfielder | Lecce | 🇿🇲Zambia | 25 | 5 | 4 | 46.2 | 33▲377.9% | 75▲12.3% |
| W. McKennieDefensive midfielder | Juventus | 🇺🇸USA | 27 | 5 | 5 | 56.6 | 55▲50.5% | 75▼7.1% |
| J. EkkelenkampAttacking midfielder | Udinese | 🇳🇱Netherlands | 26 | 5 | 3 | 46.9 | 34▲2.8% | 76±0% |
| A. BonnyCentre-forward | Inter | 🇫🇷France | 22 | 5 | 4 | 48.2 | 32▼21.2%↩ | 82▼3.4%↩ |
| S. PavlovićFull-back | AC Milan | 🇷🇸Serbia | 25 | 5 | 1 | 56.1 | 54▲64.4% | 84▲10% |
| A. AttaDefensive midfielder | Udinese | 🇫🇷France | 23 | 5 | 3 | 53 | 50▲277.9% | 86▲18.1% |
| WesleyFull-back | AS Roma | 🇧🇷Brazil | 22 | 5 | 0 | 69.2 | 71▲77.4%↩ | 91▲23%↩ |
| H. MkhitaryanCentral midfielder | Inter | 🇦🇲Armenia | 37 | 4 | 1 | 4.3 | 36▲2% | 17▼41% |
| A. BelottiCentre-forward | Cagliari | 🇮🇹Italy | 32 | 4 | 0 | 10.8 | 26▲186.8%↩ | 26▼24.1%↩ |
| C. EkubanCentre-forward | Genoa | 🇬🇭Ghana | 32 | 4 | 1 | 9 | 22▲97.3% | 27▼22.3% |
| F. BernardeschiWinger | Bologna | 🇮🇹Italy | 32 | 4 | 2 | 9.9 | 24▼38.9%↩ | 31▲14%↩ |
| M. KempfCentre-back | Como | 🇩🇪Germany | 31 | 4 | 1 | 19.9 | 52▲103.5% | 43▼18.8% |
| A. Zambo AnguissaAttacking midfielder | Napoli | 🇨🇲Cameroon | 30 | 4 | 1 | 14.3 | 28▼50.6% | 45▼35.1% |
| M'Bala NzolaCentre-forward | Pisa | 🇦🇴Angola | 29 | 4 | 1 | 16.1 | 26▼7.5%↩ | 47▼20.4%↩ |
| L. PellegriniAttacking midfielder | AS Roma | 🇮🇹Italy | 30 | 4 | 2 | 14.9 | 29▲31.5% | 48▼15.6% |
| J. BogaWinger | Juventus | 🇨🇮Côte d'Ivoire | 29 | 4 | 0 | 16.6 | 28▲128.2%↩ | 49▼13.3%↩ |
| W. CheddiraCentre-forward | Lecce | 🇲🇦Morocco | 28 | 4 | 1 | 18.5 | 21▲170.1%↩ | 50▼18.6%↩ |
| G. ManciniFull-back | AS Roma | 🇮🇹Italy | 30 | 4 | 2 | 28.4 | 73▲19.2% | 55▼15% |
| T. NoslinCentre-forward | Lazio | 🇳🇱Netherlands | 27 | 4 | 2 | 36.7 | 23▲65% | 59▼16.5% |
| BremerCentre-back | Juventus | 🇧🇷Brazil | 29 | 4 | 3 | 34.3 | 60▲261.7% | 61▲12.2% |
| R. PiccoliCentre-forward | Fiorentina | 🇮🇹Italy | 25 | 4 | 1 | 44.3 | 24▼50.9%↩ | 72▼15.1%↩ |
| K. ThorstvedtCentral midfielder | Sassuolo | 🇳🇴Norway | 27 | 4 | 4 | 60.3 | 58▲77% | 72▲10% |
| N. ŠtulićCentre-forward | Lecce | 🇷🇸Serbia | 24 | 4 | 0 | 45 | 21▼48%↩ | 73▲22.4%↩ |
| S. KılıçsoyWinger | Cagliari | 🇹🇷Türkiye | 20 | 4 | 0 | 38.8 | 16±0% | 74▲43%↩ |
| K. BowieCentre-forward | Hellas Verona | 🏴Scotland | 23 | 4 | 0 | 48 | 37▲125%↩ | 78▲61%↩ |
| M. CancellieriWinger | Lazio | 🇮🇹Italy | 24 | 4 | 2 | 48.7 | 28▲96.5%↩ | 79▲6.6%↩ |
| Alisson SantosWinger | Napoli | 🇧🇷Brazil | 23 | 4 | 0 | 50 | 30▲757.1%↩ | 81▲79.7%↩ |
| Junior MessiasWinger | Genoa | 🇧🇷Brazil | 35 | 3 | 1 | 5.3 | 20▲134.9% | 17▼7.5% |
| F. KostićAttacking midfielder | Juventus | 🇷🇸Serbia | 33 | 3 | 1 | 4.4 | 12▼62.4%↩ | 19▼25.1%↩ |
| D. ZapataCentre-forward | Torino | 🇨🇴Colombia | 35 | 3 | 1 | 5.9 | 19▲56.6% | 19▲3.3% |
| C. KabaseleCentre-back | Udinese | 🇧🇪Belgium | 35 | 3 | 0 | 8.1 | 32▲130.4% | 26▲21.3% |
| D. ZappacostaDefensive midfielder | Atalanta | 🇮🇹Italy | 34 | 3 | 3 | 8.5 | 36▲4.6% | 28▼23.3% |
| L. SpinazzolaCentral midfielder | Napoli | 🇮🇹Italy | 33 | 3 | 3 | 10.9 | 32▼7.5% | 30▼17.4% |
| R. GosensFull-back | Fiorentina | 🇩🇪Germany | 32 | 3 | 1 | 13.7 | 33▼15.7% | 36▼30.2% |
| A. BuksaCentre-forward | Udinese | 🇵🇱Poland | 30 | 3 | 0 | 11.9 | 17▼57.1%↩ | 39▲14.9%↩ |
| M. ThorsbyCentral midfielder | Genoa | 🇳🇴Norway | 30 | 3 | 1 | 13.3 | 26▲33% | 40▼25.4% |
| M. PašalićDefensive midfielder | Atalanta | 🇭🇷Croatia | 31 | 3 | 4 | 16.6 | 36±0% | 41▼25% |
| R. Loftus-CheekCentral midfielder | AC Milan | 🏴England | 30 | 3 | 1 | 12.8 | 24▲279% | 42▼15.1% |
| M. ZaccagniWinger | Lazio | 🇮🇹Italy | 31 | 3 | 0 | 12.1 | 21▼54.5% | 44▼25.9% |
| D. CataldiCentral midfielder | Lazio | 🇮🇹Italy | 32 | 3 | 3 | 20.4 | 46▲26.9%↩ | 44▼11.6%↩ |
| HermosoFull-back | AS Roma | 🇪🇸Spain | 31 | 3 | 2 | 20.7 | 59▲1102%↩ | 45▲14.4%↩ |
| A. DovbykWinger | AS Roma | 🇺🇦Ukraine | 29 | 3 | 1 | 15.9 | 23▼57.2% | 47▼32.6% |
| L. CoulibalyAttacking midfielder | Lecce | 🇲🇱Mali | 30 | 3 | 1 | 14.6 | 23▼17.8% | 47▼17.4% |
| D. DumfriesCentral midfielder | Inter | 🇳🇱Netherlands | 30 | 3 | 1 | 17.1 | 33▼1.2% | 47▼20.1% |
| David NeresWinger | Napoli | 🇧🇷Brazil | 29 | 3 | 3 | 20.8 | 37▲89.2% | 54▼13.8% |
| N. BarellaCentral midfielder | Inter | 🇮🇹Italy | 29 | 3 | 8 | 31 | 55▲19% | 59▼18.5% |
| T. PobegaCentral midfielder | Bologna | 🇮🇹Italy | 27 | 3 | 1 | 38.5 | 36▲40.7%↩ | 62▼14.8%↩ |