| M. WoledziCentre-back |  Nashville SC | 🇬🇭Ghana | 25 | 30 | 2 | 0 | 14 | 61▲24%↩ | 45▲2.8%↩ |
| AntonyCentral midfielder |  Portland Timbers | 🇧🇷Brazil | 25 | 27 | 3 | 2 | 8.8 | 35▼3.6% | 45▲1.1% |
| David Pereira da CostaAttacking midfielder | Portland Timbers | 🇵🇹Portugal | 25 | 26 | 5 | 7 | 12 | 40▲21.3% | 45▼0.9% |
| B. SchwakeGoalkeeper | Nashville SC | 🇺🇸USA | 25 | 29 | 0 | 1 | 14.1 | 62 | 45 |
| K. DenkeyCentre-forward |  FC Cincinnati | 🇹🇬Togo | 25 | 27 | 17 | 3 | 14.4 | 57▲22.3% | 47▲4% |
| M. BoguszWinger |  Houston Dynamo | 🇵🇱Poland | 25 | 29 | 8 | 1 | 11 | 28▲278.4%↩ | 48▲5.3%↩ |
| T. BoothCentre-forward |  Real Salt Lake | 🇺🇸USA | 25 | 3 | 0 | 0 | 5.9 | 4±0% | 55±0% |
| J. GómezCentre-forward |  Chicago Fire | 🇺🇸USA | 25 | 8 | 0 | 0 | 6.3 | 20±0% | 58±0% |
| J. MalatiniFull-back | FC Cincinnati | 🇦🇷Argentina | 25 | 2 | 0 | 0 | 6 | 6±0% | 59±0% |
| M. WhittakerWinger |  Colorado Rapids | 🏴England | 25 | 6 | 2 | 0 | 6.7 | 48±0% | 72±0% |
| A. PiedrahitaWinger |  Toronto FC | 🇨🇴Colombia | 24 | 1 | 0 | 0 | 6.2 | 7▼33%↩ | 31▼34%↩ |
| Roman TorresAttacking midfielder |  Minnesota United FC | 🇺🇸USA | 24 | 10 | 0 | 2 | 5.7 | 9 | 31 |
| Vinícius NogueiraFull-back |  Orlando City SC | 🇧🇷Brazil | 24 | 3 | 0 | 0 | 6.5 | 10▼63.5%↩ | 31▼32.8%↩ |
| M. LyonsFull-back |  Charlotte | 🇺🇸USA | 24 | 11 | 0 | 2 | 5.7 | 4 | 31 |
| André LuizWinger |  Sporting Kansas City | 🇧🇷Brazil | 24 | 9 | 7 | 2 | 13.3 | 0▼100%↩ | 32▼47.2%↩ |
| D. LasGoalkeeper |  Austin | 🇺🇸USA | 24 | 2 | 0 | 0 | 6 | 0▼100%↩ | 32▼2.4%↩ |
| P. StroudDefensive midfielder | Minnesota United FC | 🇺🇸USA | 24 | 1 | 0 | 0 | 6 | 0▼98.9%↩ | 32▼23.4%↩ |
| A. JacksonCentral midfielder | Minnesota United FC | 🇺🇸USA | 25 | 6 | 0 | 0 | 6.7 | 0▼100%↩ | 33▼17.1%↩ |
| K. StorlieCentre-back | Real Salt Lake | 🇺🇸USA | 24 | 0 | 0 | 0 | 6.1 | 0 | 33 |
| Jesús Rafael Barea BarrosoWinger | Real Salt Lake | 🇪🇸Spain | 24 | 3 | 0 | 0 | 6.1 | 0 | 33▼3.8% |
| B. DowdGoalkeeper | Colorado Rapids | 🇺🇸USA | 24 | 2 | 0 | 0 | 6.1 | 0 | 33 |
| C. JohnsonGoalkeeper | Columbus Crew | 🇺🇸USA | 24 | 0 | 0 | 0 | 6.2 | 0 | 33 |
| D. ChicaFull-back |  Atlanta United FC | 🇺🇸USA | 24 | 1 | 0 | 0 | 6.2 | 0 | 33 |
| N. GomisCentre-back | Toronto FC | 🇫🇷France | 24 | 9 | 0 | 0 | 6.7 | 1▼70.5% | 34▼4.8% |
| W. KumadoCentre-back |  San Diego | 🇬🇭Ghana | 24 | 2 | 0 | 0 | 6 | 0▼100% | 34▼12.2% |
| Jason ShokalookCentre-forward | Real Salt Lake | 🇺🇸USA | 24 | 13 | 0 | 0 | 6.3 | 0▼100%↩ | 34▼1.7%↩ |
| T. Ku-DiPietroDefensive midfielder | Colorado Rapids | 🇺🇸USA | 24 | 4 | 0 | 0 | 6.2 | 1▼93.5% | 34▼12.2% |
| Hosei KijimaCentral midfielder |  DC United | 🇯🇵Japan | 24 | 12 | 0 | 1 | 6.8 | 2▼79.4% | 34▼17.1% |
| Lineker RodriguesCentre-forward | Real Salt Lake | 🇧🇷Brazil | 24 | 9 | 0 | 1 | 6.5 | 0 | 34 |
| I. ParkerCentre-back |  FC Dallas | 🇺🇸USA | 24 | 0 | 0 | 0 | 6.4 | 0 | 34 |
| Maxwell MurrayCentre-back |  New York City FC | 🇺🇸USA | 24 | 2 | 0 | 0 | 6.3 | 2 | 34 |
| Tyger SmallsWinger | Charlotte | 🏴England | 24 | 15 | 0 | 0 | 6.4 | 0 | 35▲2.1% |
| H. SulteGoalkeeper | Portland Timbers | 🇺🇸USA | 24 | 15 | 0 | 0 | 6.5 | 9 | 35▼4.9% |
| Jansen MillerCentre-back | Sporting Kansas City | 🇺🇸USA | 24 | 16 | 0 | 0 | 6.7 | 4▼76.9% | 35▼13.9% |
| D. AyalaCentral midfielder |  Inter Miami | 🇦🇷Argentina | 24 | 13 | 0 | 0 | 6.7 | 4▼91.1%↩ | 35▼19.6%↩ |
| B. HidalgoFull-back |  CF Montreal | 🇺🇸USA | 24 | 4 | 0 | 0 | 6.4 | 4▼55.7%↩ | 35▼6.1%↩ |
| Ian SmithFull-back | Portland Timbers | 🇺🇸USA | 24 | 22 | 0 | 0 | 6.5 | 8▲19.4% | 36▼4.6% |
| N. MićovićGoalkeeper |  Los Angeles Galaxy | 🇷🇸Serbia | 25 | 7 | 0 | 0 | 6.8 | 2▲9.5% | 36▼7% |
| R. Ríos NovoGoalkeeper | Inter Miami | 🇦🇷Argentina | 24 | 6 | 0 | 0 | 6.7 | 4▼28.6% | 36▼6.5% |
| K. NonoAttacking midfielder | DC United | 🇯🇵Japan | 24 | 12 | 2 | 2 | 7.6 | 4▼87%↩ | 36▼30.7%↩ |
| Kenny NielsenCentre-back |  Los Angeles FC | 🇺🇸USA | 24 | 6 | 0 | 0 | 6.8 | 5▲1225% | 37▲5.2% |
| Malik HenryCentral midfielder | Toronto FC | 🇨🇦Canada | 24 | 16 | 0 | 0 | 7.2 | 5▲117.4% | 37▲4% |
| P. KingstonCentral midfielder |  Seattle Sounders | 🏳️ | 24 | 22 | 0 | 0 | 7.1 | 9 | 37▲8.6% |
| C. HarperWinger |  New York Red Bulls | 🇺🇸USA | 24 | 10 | 1 | 1 | 7 | 4▼71.1% | 37▼5.4% |
| I. BoehmerGoalkeeper |  Vancouver Whitecaps | 🇨🇦Canada | 24 | 2 | 0 | 0 | 6.9 | 5 | 37▲6.3% |
| A. AravenaCentral midfielder | Portland Timbers | 🇨🇱Chile | 24 | 19 | 1 | 0 | 7 | 8▼21%↩ | 37▼38.3%↩ |
| Antino LopezCentre-back | Seattle Sounders | 🇺🇸USA | 24 | 12 | 0 | 0 | 7 | 9 | 37▲8.4% |
| Brendan McSorleyCentre-forward |  St. Louis City | 🇺🇸USA | 24 | 12 | 1 | 0 | 7.3 | 5▼32.9% | 38▲2.2% |
| A. MightenWinger | San Diego | 🏴England | 24 | 13 | 0 | 2 | 6.7 | 9▲83.3% | 38▼2.8% |
| J. MosqueraFull-back | Portland Timbers | 🇨🇴Colombia | 24 | 3 | 1 | 1 | 6.9 | 1▼95% | 38▼10.6% |
| A. BonetigCentre-back | Portland Timbers | 🇦🇺Australia | 24 | 8 | 1 | 0 | 6.8 | 6▼34.1%↩ | 38▲126.8%↩ |
| S. BangouraDefensive midfielder |  Columbus Crew | 🇬🇳Guinea | 24 | 19 | 1 | 0 | 7.1 | 15▲57.1%↩ | 38▲4.9%↩ |
| J. CaicedoDefensive midfielder | Portland Timbers | 🇨🇴Colombia | 24 | 19 | 0 | 0 | 7.4 | 17▲34.4%↩ | 39▼17.3%↩ |
| CapitaWinger | Sporting Kansas City | 🇦🇴Angola | 24 | 17 | 2 | 1 | 7 | 17▼18.1%↩ | 39▲10.5%↩ |
| A. AnelloAttacking midfielder |  Philadelphia Union | 🇺🇸USA | 24 | 15 | 1 | 1 | 7.2 | 9▲172.7%↩ | 39▼17%↩ |
| T. CorbeanuWinger | Toronto FC | 🇨🇦Canada | 24 | 17 | 3 | 5 | 7.8 | 13▼55% | 39▼12.1% |
| Nico CavalloCentre-back | New York City FC | 🇺🇸USA | 24 | 18 | 0 | 0 | 7.4 | 16▲178% | 39▲13% |
| Loïc WilliamsCentre-back | Colorado Rapids | 🇪🇸Spain | 24 | 15 | 1 | 0 | 7.4 | 16▼54.5%↩ | 40▼37.7%↩ |
| A. IbrahimCentre-forward | Houston Dynamo | 🇳🇬Nigeria | 24 | 22 | 2 | 0 | 7.3 | 10▼34.2%↩ | 40▼2.2%↩ |
| Talles MagnoWinger | New York City FC | 🇧🇷Brazil | 24 | 18 | 2 | 2 | 7.5 | 15▲5.6%↩ | 40▼31.3%↩ |
| G. TapiaCentre-forward | Columbus Crew | 🇨🇱Chile | 24 | 6 | 1 | 1 | 7.2 | 5▼75.3%↩ | 40▼38%↩ |
| G. YowWinger |  New England Revolution | 🇺🇸USA | 24 | 22 | 1 | 0 | 7 | 8▼21.1%↩ | 40▼18.7%↩ |
| N. FernandezAttacking midfielder |  San Jose Earthquakes | 🇺🇸USA | 24 | 23 | 1 | 2 | 7.6 | 12▲785.7% | 40▲21.5% |
| P. YazbekCentral midfielder | Nashville SC | 🇦🇺Australia | 24 | 19 | 1 | 3 | 7.6 | 17▼26.2% | 40▼4.3% |
| Gabriel PiraniCentral midfielder | San Diego | 🇧🇷Brazil | 24 | 17 | 4 | 0 | 11.8 | 21▼30.9%↩ | 40▼8%↩ |
| R. PrisoCentre-back | Vancouver Whitecaps | 🇨🇦Canada | 24 | 14 | 1 | 0 | 7.5 | 18▼16.2% | 41▼1.9% |
| Jeong Sang-BinCentre-forward | St. Louis City | 🇰🇷Korea Republic | 24 | 22 | 3 | 1 | 7.8 | 15▲41.7% | 41▲14.2% |
| J. AtencioCentral midfielder | Colorado Rapids | 🇺🇸USA | 24 | 26 | 1 | 1 | 7.6 | 20▼11.7% | 41▲3% |
| J. DavisDefensive midfielder | Sporting Kansas City | 🇺🇸USA | 24 | 22 | 0 | 2 | 7.7 | 32▲141.7% | 42▲8.6% |
| K. Mboma DemCentre-forward | FC Cincinnati | 🇫🇷France | 24 | 23 | 5 | 1 | 9.2 | 28 | 42▲25.7% |
| L. LangoniWinger | New England Revolution | 🇦🇷Argentina | 24 | 21 | 3 | 6 | 7.9 | 31▲40.2% | 42▼3.2% |
| J. LukićDefensive midfielder | Philadelphia Union | 🇷🇸Serbia | 24 | 28 | 0 | 2 | 9.9 | 26▼35% | 42▼4.5% |
| B. KamungoFull-back | FC Dallas | 🇹🇿Tanzania | 24 | 20 | 0 | 2 | 8.2 | 13▼36.2% | 43▲5.7% |
| I. FrayFull-back | Inter Miami | 🇯🇲Jamaica | 24 | 22 | 1 | 2 | 7.9 | 18▲11.7% | 43▲4.2% |
| K. Kossa-RienziCentral midfielder | Seattle Sounders | 🇺🇸USA | 24 | 28 | 3 | 0 | 9.7 | 37▲97.3% | 43±0% |
| L. MunteanuCentre-forward | DC United | 🇷🇴Romania | 24 | 22 | 5 | 2 | 8 | 29▲111.5%↩ | 43▲33.9%↩ |
| M. PeltolaDefensive midfielder | DC United | 🇫🇮Finland | 24 | 28 | 1 | 0 | 9 | 33▲112.8% | 44▲10.6% |
| G. MinoungouWinger | Colorado Rapids | 🇨🇮Côte d'Ivoire | 24 | 26 | 1 | 2 | 7.8 | 14▲41.6%↩ | 44▲10.3%↩ |
| J. ForyFull-back | Portland Timbers | 🇨🇴Colombia | 24 | 28 | 0 | 3 | 8.3 | 27▲10.3% | 44▲5% |
| J. RickettsCentral midfielder | San Jose Earthquakes | 🇺🇸USA | 25 | 27 | 0 | 2 | 8.1 | 25▲51.2% | 44▲15.5% |
| PeglowWinger | DC United | 🇧🇷Brazil | 24 | 27 | 1 | 3 | 8.2 | 21▼33% | 44▲2.8% |
| T. GrayCentre-back | New York City FC | 🇯🇲Jamaica | 24 | 26 | 1 | 1 | 8.2 | 31▲5.5% | 45▲7.2% |
| B. DamianiCentre-forward | Philadelphia Union | 🇺🇾Uruguay | 24 | 30 | 12 | 3 | 14.9 | 27▼8% | 45▲2.8% |
| CalegariFull-back | Los Angeles Galaxy | 🇧🇷Brazil | 24 | 5 | 0 | 1 | 6.9 | 24▲31.9%↩ | 45▼1.1%↩ |
| Felipe AndradeCentre-back | Houston Dynamo | 🇧🇷Brazil | 24 | 22 | 1 | 0 | 13.8 | 50▲78.4% | 45▲9.2% |
| L. FarringtonWinger | FC Dallas | 🇺🇸USA | 24 | 27 | 10 | 3 | 12.2 | 42▲76.4% | 46▲6% |
| L. EnnaliCentral midfielder | Houston Dynamo | 🇩🇪Germany | 24 | 30 | 3 | 4 | 12 | 37▲173% | 49▲31.3% |
| M. GalarzaCentral midfielder | Inter Miami | 🇵🇾Paraguay | 24 | 23 | 0 | 0 | 6.9 | 17▲43.7%↩ | 50▲6.6%↩ |
| J. SkinnerCentre-back | Charlotte | 🇺🇸USA | 23 | 9 | 0 | 0 | 5.3 | 4▲3900%↩ | 28▼16.8%↩ |
| A. EssengueCentre-back | Los Angeles Galaxy | 🇨🇲Cameroon | 23 | 2 | 0 | 0 | 5.3 | 0 | 28 |
| C. PearsonCentral midfielder | St. Louis City | 🇯🇲Jamaica | 23 | 5 | 0 | 0 | 5.2 | 0 | 29 |
| L. ÁlvarezCentral midfielder | Charlotte | 🇭🇳Honduras | 23 | 5 | 0 | 1 | 5.8 | 6 | 31 |
| S. KitaharaCentral midfielder | Seattle Sounders | 🇺🇸USA | 23 | 0 | 0 | 0 | 6.4 | 0 | 33▼8.7% |
| Luke HilleDefensive midfielder | Minnesota United FC | 🇺🇸USA | 23 | 1 | 0 | 0 | 6.1 | 0 | 33 |
| N. PetkovićCentral midfielder | Seattle Sounders | 🇷🇸Serbia | 23 | 4 | 0 | 0 | 6.5 | 2▼25%↩ | 33▼8.7%↩ |
| H. OsorioCentral midfielder | Chicago Fire | 🇸🇻El Salvador | 23 | 1 | 0 | 0 | 6.3 | 0 | 34 |
| J. CasasCentral midfielder | Chicago Fire | 🇺🇸USA | 23 | 0 | 0 | 0 | 6.3 | 0▼100% | 34▼2% |
| J. DaCentre-forward | New England Revolution | 🏳️ | 23 | 1 | 0 | 0 | 6.3 | 0 | 34 |
| M. SullivanCentral midfielder | FC Cincinnati | 🇺🇸USA | 23 | 1 | 0 | 0 | 6.3 | 0 | 34 |
| F. BankCentre-forward | Toronto FC | 🏳️ | 23 | 1 | 0 | 0 | 6.3 | 0 | 34 |
