| J. TravisFull-back |  Colorado Rapids | 🇺🇸USA | 22 | 0 | 1 | 7.5 | 31▲595.6% | 43▲13% |
| K. Mboma DemCentre-forward |  FC Cincinnati | 🇫🇷France | 24 | 5 | 1 | 10.2 | 26 | 43▲27.5% |
| J. DíazCentre-back |  Minnesota United FC | 🇨🇴Colombia | 25 | 0 | 1 | 8.8 | 32▲27.1% | 43▼1.8% |
| E. AlladohCentre-forward |  Philadelphia Union | 🇬🇭Ghana | 20 | 1 | 1 | 6.7 | 13▼56.8%↩ | 43▲11.8%↩ |
| N. PalacioDefensive midfielder |  Toronto FC | 🇨🇴Colombia | 25 | 0 | 1 | 8.8 | 28▲134.5%↩ | 42▲5%↩ |
| J. HaakDefensive midfielder |  Los Angeles Galaxy | 🇺🇸USA | 24 | 0 | 1 | 9.4 | 31▼25.2%↩ | 42▼8.1%↩ |
| K. YeboahCentre-forward | Minnesota United FC | 🇮🇹Italy | 26 | 11 | 1 | 12.9 | 46▲59.2% | 42▲5% |
| N. TriantisCentral midfielder | Minnesota United FC | 🇦🇺Australia | 23 | 1 | 1 | 8.3 | 38▲447.8% | 42▲2.2% |
| Jude TerryAttacking midfielder |  Los Angeles FC | 🇺🇸USA | 17 | 1 | 1 | 5.6 | 6 | 42 |
| D. Jean-JacquesCentral midfielder | Philadelphia Union | 🇭🇹Haiti | 26 | 3 | 1 | 13.1 | 45▲22.2% | 42▲6.9% |
| AntonyCentral midfielder |  Portland Timbers | 🇧🇷Brazil | 24 | 3 | 1 | 10.2 | 20▼43.7% | 42▼7.9% |
| O. GeneCentral midfielder | Minnesota United FC | 🇫🇷France | 23 | 0 | 1 | 7.8 | 15▲202% | 42▲10% |
| B. KamungoFull-back |  FC Dallas | 🇹🇿Tanzania | 24 | 0 | 1 | 7.6 | 26▲21.4% | 42▲4% |
| Harbor MillerFull-back | Los Angeles Galaxy | 🇺🇸USA | 19 | 0 | 1 | 6.5 | 18▲307% | 42▲4.5% |
| D. PadelfordFull-back | Minnesota United FC | 🇺🇸USA | 23 | 1 | 1 | 7.8 | 12▲84.6%↩ | 41▲15.6%↩ |
| A. YusufCentral midfielder |  New England Revolution | 🇳🇬Nigeria | 26 | 5 | 1 | 13.2 | 40▲8.2% | 41±0% |
| N. StreitCentral midfielder |  CF Montreal | 🇨🇭Switzerland | 20 | 1 | 1 | 6.6 | 18 | 41 |
| Jeong Sang-BinCentre-forward |  St. Louis City | 🇰🇷Korea Republic | 24 | 2 | 1 | 7.8 | 19▲73.1% | 41▲14% |
| O. UrhoghideCentre-back | FC Dallas | 🇳🇱Netherlands | 26 | 1 | 1 | 7.5 | 27▲1.9% | 41▲4.9% |
| T. SpicerWinger |  Orlando City SC | 🇹🇹Trinidad and Tobago | 25 | 5 | 1 | 8 | 26▲42.2%↩ | 41▲2.3%↩ |
| A. QasemWinger |  Nashville SC | 🇸🇪Sweden | 23 | 2 | 1 | 7.8 | 13▲22.6% | 41▲2.3% |
| D. GjengaarCentre-forward |  New York Red Bulls | 🇳🇴Norway | 22 | 2 | 1 | 7.5 | 10▲33.3% | 40▼1.9% |
| R. AlokoWinger |  Charlotte | 🏳️ | 16 | 1 | 1 | 5.1 | 5 | 40 |
| C. WallemCentral midfielder | St. Louis City | 🇳🇴Norway | 26 | 0 | 1 | 7.5 | 27▼11.1% | 40▲6.1% |
| M. SofoAttacking midfielder | New York Red Bulls | 🇬🇭Ghana | 21 | 1 | 1 | 7 | 19±0% | 40▼9.1% |
| Nikola MarkovicFull-back |  DC United | 🇨🇦Canada | 22 | 0 | 1 | 7 | 10 | 40 |
| R. Baker-WhitingFull-back | Nashville SC | 🇺🇸USA | 21 | 1 | 1 | 9.2 | 8±0% | 40▼1.7%↩ |
| A. AnelloAttacking midfielder | Philadelphia Union | 🇺🇸USA | 24 | 1 | 1 | 7.3 | 3▼3%↩ | 40▼16%↩ |
| A. PereaCentral midfielder |  New York City FC | 🇺🇸USA | 25 | 1 | 1 | 7.5 | 29±0% | 39▼3.4% |
| Matthew EdwardsFull-back |  Atlanta United FC | 🇺🇸USA | 23 | 0 | 1 | 7.3 | 9±0% | 39▲0.5% |
| C. GarcésFull-back | Los Angeles Galaxy | 🇨🇴Colombia | 24 | 0 | 1 | 7.2 | 25▲22.8% | 39▲2.1% |
| CapitaWinger |  Sporting Kansas City | 🇦🇴Angola | 24 | 2 | 1 | 7.2 | 16▼19.6%↩ | 39▲10.3%↩ |
| A. MartínezCentre-forward | New York City FC | 🇨🇷Costa Rica | 27 | 19 | 1 | 12.8 | 59▲27.7% | 39▼12.8% |
| P. DithejaneFull-back |  Chicago Fire | 🇿🇦South Africa | 22 | 2 | 1 | 7.5 | 17▼19.9%↩ | 39▲60.8%↩ |
| J. MosqueraFull-back | Portland Timbers | 🇨🇴Colombia | 23 | 1 | 1 | 7.1 | 14±0% | 38▼11.3% |
| D. JoveljićCentre-forward |  Seattle Sounders | 🇷🇸Serbia | 27 | 10 | 1 | 5.6 | 47▼21.2%↩ | 38▲0.5%↩ |
| P. QuintonFull-back |  Real Salt Lake | 🇺🇸USA | 26 | 0 | 1 | 6.8 | 11▲40.3% | 38▲16.3% |
| Andrew GuerraCentre-forward | Portland Timbers | 🇺🇸USA | 23 | 1 | 1 | 7.5 | 3±0% | 38▲1.1% |
| Marcos Zambrano-DelgadoCentre-forward | New England Revolution | 🇺🇸USA | 21 | 0 | 1 | 6.4 | 5 | 38 |
| Marcus CaldeiraCentre-forward | Minnesota United FC | 🇨🇦Canada | 21 | 2 | 1 | 6.7 | 3 | 38 |
| Will ClearyFull-back | Charlotte | 🇺🇸USA | 23 | 0 | 1 | 7.3 | 1 | 38 |
| P. RothrockCentral midfielder | Seattle Sounders | 🇺🇸USA | 27 | 5 | 1 | 11.7 | 38▲36.3% | 37▼2.1% |
| B. VeraCentre-back | CF Montreal | 🇨🇴Colombia | 27 | 1 | 1 | 8.8 | 26▲26.2%↩ | 37▲8.8%↩ |
| N. OrdazCentre-forward | DC United | 🇸🇻El Salvador | 22 | 2 | 1 | 6.7 | 24±0% | 37▼16.4%↩ |
| V. RadojevićFull-back | Chicago Fire | 🇷🇸Serbia | 22 | 0 | 1 | 7 | 5±0% | 37▲9.8%↩ |
| Q. SullivanAttacking midfielder | Philadelphia Union | 🇺🇸USA | 22 | 0 | 1 | 6.7 | 24±0% | 37▼14.7% |
| E. EneliCentral midfielder | Real Salt Lake | 🇺🇸USA | 26 | 0 | 1 | 7.1 | 23▼37.1% | 37▼17.1% |
| K. NonoAttacking midfielder | DC United | 🇯🇵Japan | 24 | 0 | 1 | 6.8 | 32±0% | 37▼30.1%↩ |
| Guilherme BiroFull-back |  Austin | 🇧🇷Brazil | 26 | 2 | 1 | 7.1 | 26▼20.6% | 37▼10.3% |
| J. MurrellCentre-forward | DC United | 🇺🇸USA | 22 | 0 | 1 | 6.5 | 12±0% | 37▼8% |
| J. ReynoldsFull-back | Sporting Kansas City | 🇺🇸USA | 22 | 0 | 1 | 7 | 0±0% | 37▲0.5%↩ |
| G. DorseyCentral midfielder | Orlando City SC | 🇺🇸USA | 27 | 3 | 1 | 11.5 | 43▲34.2%↩ | 37▼2.1%↩ |
| S. GomezCentral midfielder | Seattle Sounders | 🇺🇸USA | 20 | 0 | 1 | 6.1 | 1 | 36 |
| N. AdimabuaWinger |  San Jose Earthquakes | 🏳️ | 25 | 0 | 1 | 6.7 | 3 | 36 |
| C. CappisCentral midfielder | FC Dallas | 🇺🇸USA | 27 | 0 | 1 | 6.8 | 24▲57% | 35▲13.5% |
| S. AfrifaWinger | Sporting Kansas City | 🇨🇦Canada | 25 | 2 | 1 | 6.7 | 0 | 35▲13.9% |
| S. KowalczykDefensive midfielder |  Houston Dynamo | 🇵🇱Poland | 28 | 1 | 1 | 3.5 | 19▼32.7% | 35▼17.9% |
| C. SabalyWinger |  Vancouver Whitecaps | 🇸🇳Senegal | 27 | 2 | 1 | 6.5 | 22▲160.2%↩ | 35▼31.6%↩ |
| M. SuleymanovCentre-forward | Sporting Kansas City | 🇷🇺Russia | 26 | 1 | 1 | 6.3 | 13▼30% | 35▼3.9% |
| M. FofanaCentre-back | New England Revolution | 🇲🇱Mali | 28 | 1 | 1 | 6.5 | 38▼15% | 35▲4.2% |
| W. Abou AliCentre-forward |  Columbus Crew | 🇩🇰Denmark | 27 | 5 | 1 | 7.4 | 8±0% | 34▲13% |
| D. PorębaAttacking midfielder | Chicago Fire | 🇺🇸USA | 23 | 0 | 1 | 7 | 0±0% | 34▲7.3%↩ |
| M. NavarroFull-back | Colorado Rapids | 🇻🇪Venezuela | 27 | 0 | 1 | 11.3 | 26▼21%↩ | 33▼18.2%↩ |
| D. PereiraCentral midfielder | CF Montreal | 🇻🇪Venezuela | 26 | 0 | 1 | 6.2 | 30±0% | 33▼18.5%↩ |
| M. HerreraCentral midfielder | Columbus Crew | 🇦🇷Argentina | 27 | 0 | 1 | 5.9 | 18▲26.2% | 32▼5.8% |
| L. BarrazaGoalkeeper |  Inter Miami | 🇺🇸USA | 29 | 0 | 1 | 3.3 | 4 | 32▲19.2%↩ |
| S. MooreCentre-back | FC Dallas | 🇺🇸USA | 29 | 1 | 1 | 4.4 | 28▲10.2% | 32▲1.6% |
| N. ToloCentre-back | Seattle Sounders | 🇨🇲Cameroon | 29 | 0 | 1 | 5.2 | 40▲66.4% | 31▲5.8% |
| N. TafariFull-back | Los Angeles FC | 🇺🇸USA | 29 | 0 | 1 | 5.1 | 58▲87.9% | 31▲10% |
| M. AmundsenFull-back | Columbus Crew | 🇩🇰Denmark | 28 | 0 | 1 | 3.8 | 25▲32.5% | 31▲1% |
| Ž. KolmaničFull-back | Austin | 🇸🇮Slovenia | 26 | 0 | 1 | 6.1 | 8±0% | 30▼14.8% |
| Rafael SantosCentral midfielder | St. Louis City | 🇧🇷Brazil | 28 | 1 | 1 | 3.6 | 21▲86.6%↩ | 30▲5.6%↩ |
| A. MățanWinger | St. Louis City | 🇷🇴Romania | 27 | 0 | 1 | 5.3 | 35±0% | 30▼10.2%↩ |
| Y. TakaokaGoalkeeper | Vancouver Whitecaps | 🇯🇵Japan | 30 | 0 | 1 | 4.7 | 47▲33.1% | 30▼1% |
| D. DianiDefensive midfielder | Charlotte | 🇫🇷France | 28 | 0 | 1 | 3.3 | 19▲18.6% | 30▲4.9% |
| A. O'NeillDefensive midfielder | New York City FC | 🇦🇺Australia | 28 | 0 | 1 | 3.9 | 40▲189.2% | 30±0% |
| L. de la TorreCentral midfielder | Charlotte | 🇺🇸USA | 28 | 0 | 1 | 3.2 | 13▼56.8%↩ | 29▼15.3%↩ |
| L. DíazWinger | New England Revolution | 🇨🇷Costa Rica | 27 | 0 | 1 | 5.6 | 3 | 28▼15.7%↩ |
| J. GladFull-back | Real Salt Lake | 🇺🇸USA | 29 | 0 | 1 | 2.6 | 14▼50% | 27▼10.5% |
| B. VázquezCentre-forward | Austin | 🇺🇸USA | 27 | 0 | 1 | 5.4 | 18±0% | 27▼20.5% |
| T. NtsabelengCentral midfielder | FC Dallas | 🇿🇦South Africa | 28 | 0 | 1 | 3.2 | 7▼51.7% | 27▼19.6% |
| B. ŠabovićCentral midfielder | Austin | 🇸🇪Sweden | 28 | 0 | 1 | 3.1 | 13▼29.1% | 27▼10% |
| J. ElliottCentre-back | Chicago Fire | 🏴England | 31 | 0 | 1 | 3.3 | 33▲32.9% | 27▲4.7% |
| K. HiebertCentre-back | St. Louis City | 🇨🇦Canada | 29 | 1 | 1 | 3.3 | 14▼12.3% | 27▼16.1% |
| D. EtienneCentre-forward | Toronto FC | 🇭🇹Haiti | 29 | 3 | 1 | 3.5 | 14▲13.9% | 26▲8.2% |
| J. GallagherCentre-back | Austin | 🇮🇪Republic of Ireland | 30 | 0 | 1 | 2.5 | 24▲17.5% | 26▼1.1% |
| S. JunquaFull-back | Real Salt Lake | 🇺🇸USA | 29 | 0 | 1 | 2.6 | 9▼42.9% | 26▼3.8% |
| ArturDefensive midfielder | Houston Dynamo | 🇧🇷Brazil | 30 | 0 | 1 | 3.5 | 28▼5.2% | 24▼10.1% |
| S. SpieringsDefensive midfielder | Real Salt Lake | 🇳🇱Netherlands | 30 | 1 | 1 | 3.6 | 32▲78.5%↩ | 24▲13.7%↩ |
| R. LaryeaFull-back | Toronto FC | 🇨🇦Canada | 31 | 2 | 1 | 2.2 | 19▲3.3% | 23▲25.7% |
| A. MuylCentral midfielder | Nashville SC | 🇺🇸USA | 30 | 0 | 1 | 2.4 | 17▼42.5% | 22▼14.2% |
| C. RoldanAttacking midfielder | Seattle Sounders | 🇺🇸USA | 31 | 3 | 1 | 2.8 | 38▼5% | 21▼14.6% |
| L. MacNaughtonFull-back | St. Louis City | 🇨🇦Canada | 31 | 1 | 1 | 1.7 | 12▲123.6%↩ | 21▲25.9%↩ |
| J. PalaciosFull-back | Nashville SC | 🇨🇴Colombia | 32 | 1 | 1 | 2.5 | 44▲90.9% | 20▲9.9% |
| J. OrtizCentral midfielder | Portland Timbers | 🇪🇨Ecuador | 30 | 0 | 1 | 1.9 | 7±0% | 20▼0.5% |
| M. MiazgaFull-back | FC Cincinnati | 🇺🇸USA | 31 | 0 | 1 | 1.6 | 9▼54.8% | 20▼2.9% |
| A. Saint-MaximinWinger | Charlotte | 🇫🇷France | 29 | 0 | 1 | 2.2 | 16▲17%↩ | 20▼31.5%↩ |
| A. BouzatCentral midfielder | Houston Dynamo | 🇦🇷Argentina | 32 | 1 | 1 | 2.3 | 26▼26.7%↩ | 19▼23.4%↩ |
| R. LodCentral midfielder | Chicago Fire | 🇫🇮Finland | 33 | 4 | 1 | 1.8 | 31▼30.4%↩ | 17▼14.4%↩ |
| B. AcostaAttacking midfielder | Nashville SC | 🇭🇳Honduras | 32 | 3 | 1 | 2 | 16▲327% | 16▲35.8% |
