| N. GudeljCentral midfielder | Getafe | 🇷🇸Serbia | 34 | 6 | 0 | 0 | 3.2 | 31±0% | 26±0% |
| A. RüdigerCentre-back | Real Madrid | 🇩🇪Germany | 33 | 4 | 1 | 0 | 7.7 | 21±0% | 25±0% |
| BigasCentre-back | Elche | 🇪🇸Spain | 36 | 4 | 0 | 0 | 2.4 | 27±0% | 25±0% |
| Kiko FemeníaCentral midfielder | Getafe | 🇪🇸Spain | 35 | 4 | 0 | 0 | 2.6 | 33±0% | 25±0% |
| Marc BartraCentre-back | Real Betis | 🇪🇸Spain | 35 | 5 | 1 | 0 | 5.5 | 35±0% | 25±0% |
| RaílloCentre-back | Mallorca | 🇪🇸Spain | 35 | 10 | 1 | 0 | 3.8 | 40▲85.3% | 23±0% |
| G. CabezasCentral midfielder | Athletic Club | 🇨🇴Colombia | 23 | 11 | 0 | 0 | 15.3 | 3 | 23 |
| Diego LlorenteCentre-back | Real Betis | 🇪🇸Spain | 33 | 4 | 0 | 0 | 7.3 | 24±0% | 23±0% |
| D. FoulquierFull-back | Valencia | 🇬🇵Guadeloupe | 33 | 15 | 0 | 0 | 8.4 | 11▼52% | 22▼45.4% |
| Fábio CardosoCentre-back | Sevilla | 🇵🇹Portugal | 32 | 4 | 0 | 0 | 6.6 | 4▼77.5%↩ | 22▼40%↩ |
| Gerard MorenoWinger | Villarreal | 🇪🇸Spain | 34 | 8 | 2 | 0 | 7.8 | 33±0% | 22±0% |
| Alberto MorenoCentre-back | Mallorca | 🇪🇸Spain | 34 | 4 | 0 | 0 | 2 | 7▼75.7%↩ | 20±0% |
| L. SosaCentre-back | Barcelona | 🇪🇨Ecuador | 32 | 12 | 0 | 0 | 14.4 | 10 | 20 |
| J. IntriagoCentral midfielder | Barcelona | 🇪🇨Ecuador | 30 | 2 | 0 | 0 | 10.3 | 0▼95.8%↩ | 19▼37.8%↩ |
| JuanmiCentre-forward | Getafe | 🇪🇸Spain | 33 | 8 | 1 | 0 | 4 | 4 | 17▼45.6% |
| M. DituroGoalkeeper | Elche | 🇦🇷Argentina | 39 | 9 | 0 | 0 | 2.6 | 12±0% | 17±0% |
| W. SzczęsnyGoalkeeper | Barcelona | 🇵🇱Poland | 36 | 1 | 0 | 0 | 3.8 | 12±0% | 16±0% |
| D. LivakovićGoalkeeper | Barcelona | 🇭🇷Croatia | 31 | 1 | 0 | 0 | 13.5 | 0▼100%↩ | 16▼6%↩ |
| I. BalliuCentre-back | Rayo Vallecano | 🇦🇱Albania | 34 | 7 | 0 | 0 | 2.7 | 11±0% | 15±0% |
| Juan CruzCentre-back | Oviedo | 🇪🇸Spain | 34 | 6 | 0 | 0 | 2.6 | 16▲297.5%↩ | 14±0% |
| Abdón PratsCentre-forward | Mallorca | 🇪🇸Spain | 33 | 15 | 0 | 0 | 1.9 | 0▼100% | 14▼52.4% |
| IscoAttacking midfielder | Real Betis | 🇪🇸Spain | 34 | 8 | 2 | 0 | 5 | 6±0% | 14±0% |
| PortuCentre-forward | Girona | 🇪🇸Spain | 34 | 1 | 0 | 0 | 1.1 | 0 | 13±0% |
| Iago AspasCentre-forward | Celta Vigo | 🇪🇸Spain | 39 | 6 | 1 | 0 | 1.9 | 25±0% | 13±0% |
| David LópezCentre-back | Girona | 🇪🇸Spain | 37 | 6 | 0 | 0 | 1.4 | 15▲317.1% | 12▲126.9% |
| Aitor FernándezGoalkeeper | Osasuna | 🇪🇸Spain | 35 | 3 | 0 | 0 | 2.8 | 0 | 11±0% |
| D. BenedettoCentre-forward | Barcelona | 🇦🇷Argentina | 36 | 8 | 0 | 0 | 3.1 | 0 | 9▲13.3%↩ |
| C. StuaniCentre-forward | Girona | 🇺🇾Uruguay | 40 | 2 | 0 | 0 | 0.3 | 0▼100% | 7±0% |
| AdriánGoalkeeper | Real Betis | 🇪🇸Spain | 39 | 1 | 0 | 0 | 0.8 | 0▼100% | 4▼73.7% |
| Iván CuéllarGoalkeeper | Mallorca | 🇪🇸Spain | 42 | 1 | 0 | 0 | 0.4 | 0▼100%↩ | 4▼70.7%↩ |
| Y. DiomandeWinger | Real Madrid | 🇨🇮Côte d'Ivoire | 19 | 8 | 1 | 1 | 72.5 | 65±0% | 97▲3.7%↩ |
| G. MikautadzeWinger | Villarreal | 🇬🇪Georgia | 26 | 9 | 2 | 1 | 79.7 | 56±0% | 86±0% |
| PedriCentral midfielder | Barcelona | 🇪🇸Spain | 23 | 9 | 1 | 1 | 92 | 34±0% | 86±0% |
| O. El HilaliFull-back | Espanyol | 🇲🇦Morocco | 23 | 8 | 0 | 1 | 50.6 | 45±0% | 85▲1.7% |
| Renato VeigaFull-back | Villarreal | 🇵🇹Portugal | 23 | 8 | 0 | 1 | 84.2 | 26±0% | 85±0% |
| R. BardghjiCentral midfielder | Barcelona | 🇸🇪Sweden | 20 | 21 | 1 | 1 | 81.5 | 10 | 83▲110.2%↩ |
| Adrian LisoWinger | Mallorca | 🇪🇸Spain | 21 | 10 | 0 | 1 | 23.5 | 0▼100%↩ | 82±0% |
| BarrenetxeaWinger | Real Sociedad | 🇪🇸Spain | 24 | 7 | 2 | 1 | 84.3 | 27±0% | 80±0% |
| Félix CorreiaWinger | Sevilla | 🇵🇹Portugal | 25 | 4 | 1 | 1 | 47.2 | 34±0% | 80▲1.9%↩ |
| Etta EyongCentre-forward | Levante | 🇨🇲Cameroon | 23 | 3 | 0 | 1 | 42.8 | 35±0% | 80▲1.8% |
| Diego LópezCentral midfielder | Valencia | 🇪🇸Spain | 24 | 34 | 4 | 1 | 50.5 | 30▼34.9% | 79▼10.8% |
| Pablo BarriosCentral midfielder | Atletico Madrid | 🇪🇸Spain | 23 | 6 | 0 | 1 | 84.5 | 24±0% | 79±0% |
| O. VargasCentral midfielder | Atletico Madrid | 🇺🇸USA | 21 | 12 | 0 | 1 | 83.4 | 39▲15.2%↩ | 78▲64.8%↩ |
| Lee Kang-InAttacking midfielder | Atletico Madrid | 🇰🇷Korea Republic | 25 | 9 | 2 | 1 | 85.8 | 26±0% | 77±0% |
| V. VanatCentre-forward | Girona | 🇺🇦Ukraine | 24 | 5 | 1 | 1 | 25.1 | 11▼70.7% | 77±0% |
| J. ÁlvarezWinger | Atletico Madrid | 🇦🇷Argentina | 26 | 5 | 0 | 1 | 68.8 | 39±0% | 77±0% |
| Daniel YañezWinger | Real Madrid | 🇪🇸Spain | 19 | 2 | 0 | 1 | 67.2 | 2 | 76▲6.4% |
| M. SatrianoWinger | Getafe | 🇺🇾Uruguay | 25 | 8 | 1 | 1 | 46.4 | 27±0% | 76±0% |
| Javier BoñarFull-back | Girona | 🇪🇸Spain | 21 | 7 | 0 | 1 | 24.3 | 18▲408.3%↩ | 75±0% |
| T. ParrottWinger | Real Betis | 🇮🇪Republic of Ireland | 24 | 6 | 1 | 1 | 49.3 | 62±0% | 74±0% |
| Sergio CamelloWinger | Rayo Vallecano | 🇪🇸Spain | 25 | 8 | 7 | 1 | 50.5 | 20±0% | 74±0% |
| Hugo DuroCentre-forward | Valencia | 🇪🇸Spain | 26 | 9 | 0 | 1 | 38.9 | 38±0% | 74±0% |
| I. KamateCentral midfielder | Atletico Madrid | 🇫🇷France | 22 | 1 | 0 | 1 | 79.1 | 5 | 73 |
| S. SanchezAttacking midfielder | Athletic Club | 🏳️ | 18 | 7 | 0 | 1 | 37 | 3 | 73 |
| Christantus UcheWinger | Getafe | 🇪🇸Spain | 23 | 3 | 1 | 1 | 47.1 | 6▼82.8% | 72▼18.6% |
| J. CardosoCentral midfielder | Atletico Madrid | 🇺🇸USA | 25 | 6 | 0 | 1 | 78.8 | 12±0% | 72▲3% |
| J. KoundéFull-back | Barcelona | 🇫🇷France | 27 | 6 | 1 | 1 | 69 | 47±0% | 71±0% |
| Álex SánchezWinger | Elche | 🏳️ | 19 | 1 | 0 | 1 | 36.9 | 1 | 71 |
| Arnau TenasGoalkeeper | Mallorca | 🇪🇸Spain | 25 | 10 | 0 | 1 | 33.6 | 43▲890.7%↩ | 71±0% |
| Marcos FernándezCentre-forward | Espanyol | 🇪🇸Spain | 23 | 8 | 1 | 1 | 48.2 | 47±0% | 70±0% |
| Raúl GarcíaWinger | Osasuna | 🇪🇸Spain | 25 | 8 | 1 | 1 | 47.6 | 26±0% | 70±0% |
| Iván AzónCentre-forward | Getafe | 🇪🇸Spain | 23 | 5 | 1 | 1 | 47.3 | 28▲17%↩ | 69±0% |
| Marc DomenechCentre-forward | Atletico Madrid | 🇪🇸Spain | 19 | 7 | 0 | 1 | 61.6 | 3 | 69▼2.8%↩ |
| Rafel BauzàAttacking midfielder | Espanyol | 🇪🇸Spain | 21 | 4 | 0 | 1 | 42.6 | 44±0% | 69±0% |
| David JiménezFull-back | Oviedo | 🇪🇸Spain | 22 | 5 | 0 | 1 | 24.1 | 8▲7600%↩ | 69±0% |
| Víctor ChustFull-back | Elche | 🇪🇸Spain | 26 | 9 | 0 | 1 | 44.2 | 31±0% | 69±0% |
| Iker LosadaCentre-forward | Real Betis | 🇪🇸Spain | 25 | 23 | 3 | 1 | 47.5 | 15▲228.9%↩ | 68▼4.9%↩ |
| Jon Ander OlasagastiCentral midfielder | Levante | 🇪🇸Spain | 26 | 9 | 1 | 1 | 43.9 | 32±0% | 68±0% |
| IsaacCentre-forward | Sevilla | 🇪🇸Spain | 26 | 7 | 2 | 1 | 45.1 | 18±0% | 67±0% |
| Iván MoranteCentral midfielder | Girona | 🇪🇸Spain | 25 | 7 | 0 | 1 | 24 | 11▼73.5%↩ | 67±0% |
| Y. FofanaAttacking midfielder | Sevilla | 🇫🇷France | 27 | 5 | 1 | 1 | 39.7 | 35±0% | 67±0% |
| E. BardeliAttacking midfielder | Levante | 🇫🇷France | 25 | 8 | 1 | 1 | 46.3 | 49±0% | 67±0% |
| Fran GarcíaFull-back | Real Betis | 🇪🇸Spain | 27 | 8 | 0 | 1 | 41.9 | 17±0% | 65▲11.2%↩ |
| J. de HaasFull-back | Valencia | 🇳🇱Netherlands | 26 | 5 | 0 | 1 | 40.5 | 71±0% | 64▲2.7%↩ |
| P. RatkovCentre-forward | Levante | 🇷🇸Serbia | 23 | 4 | 0 | 1 | 43.3 | 0▼100%↩ | 64▲36.9%↩ |
| T. Alexander-ArnoldFull-back | Real Madrid | 🏴England | 28 | 5 | 0 | 1 | 34 | 20±0% | 64▲12.4% |
| Mikel GotiAttacking midfielder | Oviedo | 🇪🇸Spain | 24 | 5 | 1 | 1 | 25.1 | 11▲4.9%↩ | 63▲10.5%↩ |
| N. DeossaCentral midfielder | Real Betis | 🇨🇴Colombia | 26 | 9 | 0 | 1 | 43.3 | 5±0% | 62±0% |
| Carles AleñáAttacking midfielder | Alaves | 🇪🇸Spain | 28 | 6 | 0 | 1 | 18.8 | 28±0% | 57±0% |
| Fran BeltránCentral midfielder | Girona | 🇪🇸Spain | 27 | 8 | 1 | 1 | 21.7 | 19▼4.4% | 57±0% |
| V. MingoCentre-forward | Oviedo | 🏳️ | 22 | 7 | 0 | 1 | 22.8 | 5 | 57 |
| Jorge de FrutosCentral midfielder | Rayo Vallecano | 🇪🇸Spain | 29 | 6 | 0 | 1 | 15.6 | 42±0% | 56±0% |
| Tomás MendesCentral midfielder | Alaves | 🇪🇸Spain | 21 | 5 | 0 | 1 | 33.5 | 5 | 56 |
| Pablo FornalsCentral midfielder | Real Betis | 🇪🇸Spain | 30 | 8 | 0 | 1 | 13.9 | 51±0% | 56±0% |
| Éder MilitãoFull-back | Real Madrid | 🇧🇷Brazil | 28 | 16 | 2 | 1 | 52.6 | 24±0% | 55±0% |
| K. LomónacoCentre-back | Elche | 🇦🇷Argentina | 24 | 24 | 0 | 1 | 53.5 | 34▼45.2%↩ | 54▼0.6%↩ |
| Álex GrimaldoFull-back | Atletico Madrid | 🇪🇸Spain | 31 | 8 | 3 | 1 | 22.8 | 34±0% | 54▲12.1%↩ |
| Abel RuizCentre-forward | Girona | 🇪🇸Spain | 26 | 8 | 2 | 1 | 22.9 | 16 | 53±0% |
| SiveraGoalkeeper | Alaves | 🇪🇸Spain | 30 | 8 | 0 | 1 | 13.8 | 7±0% | 53±0% |
| Adrià PedrosaFull-back | Rayo Vallecano | 🇪🇸Spain | 28 | 6 | 1 | 1 | 20.3 | 20±0% | 52▲5.9%↩ |
| Marc RocaDefensive midfielder | Real Betis | 🇪🇸Spain | 29 | 6 | 0 | 1 | 17.2 | 27±0% | 52±0% |
| Gonzalo VillarCentral midfielder | Elche | 🇪🇸Spain | 28 | 9 | 0 | 1 | 20.9 | 10±0% | 48±0% |
| Aritz AldasoroAttacking midfielder | Oviedo | 🇪🇸Spain | 27 | 5 | 0 | 1 | 18.5 | 5▼28.8%↩ | 48▲8.1%↩ |
| Ãlvaro SantosCentral midfielder | Atletico Madrid | 🇪🇸Spain | 21 | 28 | 1 | 1 | 46.8 | 10▼45.3%↩ | 47▲1.1%↩ |
| Vladimir SilvaWinger | Celta Vigo | 🏳️ | 16 | 26 | 1 | 1 | 19.5 | 5±0% | 45▲0.7%↩ |
| Bernardo SilvaCentral midfielder | Real Madrid | 🇵🇹Portugal | 32 | 6 | 0 | 1 | 11.4 | 45±0% | 45±0% |
| G. KochorashviliCentral midfielder | Sevilla | 🇬🇪Georgia | 27 | 6 | 0 | 1 | 37.2 | 11±0% | 45±0% |
| G. Lo CelsoAttacking midfielder | Real Betis | 🇦🇷Argentina | 30 | 2 | 0 | 1 | 11.6 | 24±0% | 44±0% |
| CatenaFull-back | Osasuna | 🇪🇸Spain | 32 | 7 | 0 | 1 | 10.5 | 31±0% | 44±0% |
| Marcos LlorenteDefensive midfielder | Atletico Madrid | 🇪🇸Spain | 31 | 9 | 0 | 1 | 17.9 | 40±0% | 43±0% |