| Matthew EdwardsFull-back |  Atlanta United FC | 🇺🇸USA | 23 | 20 | 0 | 1 | 7.1 | 7▼14.1% | 39▲0.5% |
| A. FortuneAttacking midfielder | Atlanta United FC | 🇹🇹Trinidad and Tobago | 23 | 16 | 3 | 0 | 7.3 | 10▼14.2% | 39▲1.3% |
| E. WynderCentral midfielder |  Los Angeles Galaxy | 🇺🇸USA | 23 | 20 | 0 | 0 | 7.2 | 11▼24.8% | 39▲4% |
| Will ClearyFull-back |  Charlotte | 🇺🇸USA | 23 | 13 | 0 | 1 | 7.3 | 5 | 39 |
| J. AudeCentre-back | Los Angeles Galaxy | 🇦🇷Argentina | 23 | 18 | 0 | 0 | 7.3 | 16▲63.3% | 39▲4.3% |
| Andrew GuerraCentre-forward |  Portland Timbers | 🇺🇸USA | 23 | 11 | 1 | 2 | 7.4 | 8▲211.1% | 38▲2.7% |
| William ReillyCentral midfielder | Atlanta United FC | 🇺🇸USA | 23 | 11 | 0 | 0 | 7.6 | 7▼17.2% | 38▲1.6% |
| A. AlvaradoCentre-forward |  San Diego | 🇺🇸USA | 23 | 21 | 1 | 0 | 7 | 6▲8.6% | 38±0% |
| B. TraoréWinger |  New York City FC | 🇨🇮Côte d'Ivoire | 23 | 15 | 1 | 0 | 7.9 | 6▼80.4%↩ | 38▼21%↩ |
| A. LopezCentre-back |  Seattle Sounders | 🏳️ | 23 | 12 | 0 | 0 | 7.4 | 12 | 38 |
| G. MartínezCentre-back |  Philadelphia Union | 🇨🇴Colombia | 23 | 7 | 0 | 0 | 6.8 | 9 | 37 |
| D. PorębaAttacking midfielder |  Chicago Fire | 🇺🇸USA | 23 | 3 | 0 | 1 | 7 | 3▲1300%↩ | 37▲18.1%↩ |
| M. FlorianiCentre-back |  San Jose Earthquakes | 🇺🇸USA | 23 | 9 | 0 | 0 | 7 | 8▼14.6% | 37▲0.5% |
| T. KarumanchiDefensive midfielder |  Columbus Crew | 🏳️ | 23 | 10 | 0 | 0 | 6.9 | 6 | 37 |
| G. FloresCentre-back |  FC Cincinnati | 🇵🇾Paraguay | 23 | 7 | 0 | 0 | 6.6 | 4▼81.8% | 36▼13.8% |
| G. DillonCentral midfielder |  Real Salt Lake | 🇺🇸USA | 23 | 10 | 0 | 0 | 6.6 | 4 | 36 |
| I. PilcherCentre-back | San Diego | 🇺🇸USA | 23 | 11 | 0 | 0 | 6.6 | 5▼66.9% | 36▼13.8% |
| A. SiebWinger |  Los Angeles FC | 🇩🇪Germany | 23 | 8 | 1 | 0 | 7.5 | 0▼100%↩ | 35▼49.2%↩ |
| M. FallCentre-back |  St. Louis City | 🇸🇳Senegal | 23 | 3 | 0 | 0 | 6.6 | 0▼100%↩ | 35▼3.1%↩ |
| Jorge AlastueyCentral midfielder |  Austin | 🇪🇸Spain | 23 | 13 | 0 | 0 | 6.6 | 4 | 35 |
| A. FarnosWinger | New York City FC | 🏳️ | 23 | 8 | 0 | 0 | 6.5 | 0 | 35 |
| Javier OteroGoalkeeper |  Orlando City SC | 🇻🇪Venezuela | 23 | 2 | 0 | 0 | 6.6 | 0 | 35▲0.6% |
| J. VilsaintWinger |  Toronto FC | 🇨🇦Canada | 23 | 4 | 0 | 0 | 6.4 | 0▼100%↩ | 35▼9.2%↩ |
| C. ClarkAttacking midfielder | Seattle Sounders | 🇺🇸USA | 23 | 13 | 1 | 0 | 7.2 | 2▼90%↩ | 34▼18.5%↩ |
| M. ĐorđevićCentre-back | Austin | 🇷🇸Serbia | 23 | 7 | 0 | 0 | 6.4 | 5▲96.2% | 34▼5% |
| Kieran SargeantFull-back | San Diego | 🇺🇸USA | 23 | 21 | 1 | 1 | 7.5 | 14±0% | 34▲2.4%↩ |
| D. PadelfordFull-back | New York Red Bulls | 🇺🇸USA | 23 | 18 | 1 | 1 | 8.7 | 1▼90.8%↩ | 34▼4.5%↩ |
| D. SealyWinger |  CF Montreal | 🇺🇸USA | 23 | 21 | 0 | 2 | 6.7 | 0▼100% | 34▼25.3% |
| J. GainesCentre-back |  Nashville SC | 🇺🇸USA | 23 | 3 | 0 | 0 | 6.4 | 2▼72.2% | 34▼4.5% |
| M. SullivanCentral midfielder | FC Cincinnati | 🇺🇸USA | 23 | 1 | 0 | 0 | 6.3 | 0 | 34 |
| F. BankCentre-forward | Toronto FC | 🏳️ | 23 | 1 | 0 | 0 | 6.3 | 0 | 34 |
| H. OsorioCentral midfielder | Chicago Fire | 🇸🇻El Salvador | 23 | 1 | 0 | 0 | 6.3 | 0 | 34 |
| J. CasasCentral midfielder | Chicago Fire | 🇺🇸USA | 23 | 0 | 0 | 0 | 6.3 | 0▼100% | 34▼2% |
| J. DaCentre-forward |  New England Revolution | 🏳️ | 23 | 1 | 0 | 0 | 6.3 | 0 | 34 |
| N. PetkovićCentral midfielder | Seattle Sounders | 🇷🇸Serbia | 23 | 4 | 0 | 0 | 6.5 | 2▼25%↩ | 33▼8.7%↩ |
| Luke HilleDefensive midfielder |  Minnesota United FC | 🇺🇸USA | 23 | 1 | 0 | 0 | 6.1 | 0 | 33 |
| S. KitaharaCentral midfielder | Seattle Sounders | 🇺🇸USA | 23 | 0 | 0 | 0 | 6.4 | 0 | 33▼8.7% |
| L. ÁlvarezCentral midfielder | Charlotte | 🇭🇳Honduras | 23 | 5 | 0 | 1 | 5.8 | 6 | 31 |
| C. PearsonCentral midfielder | St. Louis City | 🇯🇲Jamaica | 23 | 5 | 0 | 0 | 5.2 | 0 | 29 |
| A. EssengueCentre-back | Los Angeles Galaxy | 🇨🇲Cameroon | 23 | 2 | 0 | 0 | 5.3 | 0 | 28 |
| J. SkinnerCentre-back | Charlotte | 🇺🇸USA | 23 | 9 | 0 | 0 | 5.3 | 4▲3900%↩ | 28▼16.8%↩ |
| M. GalarzaCentral midfielder |  Inter Miami | 🇵🇾Paraguay | 24 | 23 | 0 | 0 | 6.9 | 17▲43.7%↩ | 50▲6.6%↩ |
| L. EnnaliCentral midfielder |  Houston Dynamo | 🇩🇪Germany | 24 | 30 | 3 | 4 | 12 | 37▲173% | 49▲31.3% |
| L. FarringtonWinger |  FC Dallas | 🇺🇸USA | 24 | 27 | 10 | 3 | 12.2 | 42▲76.4% | 46▲6% |
| Felipe AndradeCentre-back | Houston Dynamo | 🇧🇷Brazil | 24 | 22 | 1 | 0 | 13.8 | 50▲78.4% | 45▲9.2% |
| B. DamianiCentre-forward | Philadelphia Union | 🇺🇾Uruguay | 24 | 30 | 12 | 3 | 14.9 | 27▼8% | 45▲2.8% |
| CalegariFull-back | Los Angeles Galaxy | 🇧🇷Brazil | 24 | 5 | 0 | 1 | 6.9 | 24▲31.9%↩ | 45▼1.1%↩ |
| T. GrayCentre-back | New York City FC | 🇯🇲Jamaica | 24 | 26 | 1 | 1 | 8.2 | 31▲5.5% | 45▲7.2% |
| PeglowWinger |  DC United | 🇧🇷Brazil | 24 | 27 | 1 | 3 | 8.2 | 21▼33% | 44▲2.8% |
| J. RickettsCentral midfielder | San Jose Earthquakes | 🇺🇸USA | 25 | 27 | 0 | 2 | 8.1 | 25▲51.2% | 44▲15.5% |
| G. MinoungouWinger |  Colorado Rapids | 🇨🇮Côte d'Ivoire | 24 | 26 | 1 | 2 | 7.8 | 14▲41.6%↩ | 44▲10.3%↩ |
| J. ForyFull-back | Portland Timbers | 🇨🇴Colombia | 24 | 28 | 0 | 3 | 8.3 | 27▲10.3% | 44▲5% |
| M. PeltolaDefensive midfielder | DC United | 🇫🇮Finland | 24 | 28 | 1 | 0 | 9 | 33▲112.8% | 44▲10.6% |
| L. MunteanuCentre-forward | DC United | 🇷🇴Romania | 24 | 22 | 5 | 2 | 8 | 29▲111.5%↩ | 43▲33.9%↩ |
| K. Kossa-RienziCentral midfielder | Seattle Sounders | 🇺🇸USA | 24 | 28 | 3 | 0 | 9.7 | 37▲97.3% | 43±0% |
| I. FrayFull-back | Inter Miami | 🇯🇲Jamaica | 24 | 22 | 1 | 2 | 7.9 | 18▲11.7% | 43▲4.2% |
| B. KamungoFull-back | FC Dallas | 🇹🇿Tanzania | 24 | 20 | 0 | 2 | 8.2 | 13▼36.2% | 43▲5.7% |
| J. LukićDefensive midfielder | Philadelphia Union | 🇷🇸Serbia | 24 | 28 | 0 | 2 | 9.9 | 26▼35% | 42▼4.5% |
| K. Mboma DemCentre-forward | FC Cincinnati | 🇫🇷France | 24 | 23 | 5 | 1 | 9.2 | 28 | 42▲25.7% |
| L. LangoniWinger | New England Revolution | 🇦🇷Argentina | 24 | 21 | 3 | 6 | 7.9 | 31▲40.2% | 42▼3.2% |
| J. DavisDefensive midfielder |  Sporting Kansas City | 🇺🇸USA | 24 | 22 | 0 | 2 | 7.7 | 32▲141.7% | 42▲8.6% |
| J. AtencioCentral midfielder | Colorado Rapids | 🇺🇸USA | 24 | 26 | 1 | 1 | 7.6 | 20▼11.7% | 41▲3% |
| R. PrisoCentre-back |  Vancouver Whitecaps | 🇨🇦Canada | 24 | 14 | 1 | 0 | 7.5 | 18▼16.2% | 41▼1.9% |
| Jeong Sang-BinCentre-forward | St. Louis City | 🇰🇷Korea Republic | 24 | 22 | 3 | 1 | 7.8 | 15▲41.7% | 41▲14.2% |
| P. YazbekCentral midfielder | Nashville SC | 🇦🇺Australia | 24 | 19 | 1 | 3 | 7.6 | 17▼26.2% | 40▼4.3% |
| Gabriel PiraniCentral midfielder | San Diego | 🇧🇷Brazil | 24 | 17 | 4 | 0 | 11.8 | 21▼30.9%↩ | 40▼8%↩ |
| N. FernandezAttacking midfielder | San Jose Earthquakes | 🇺🇸USA | 24 | 23 | 1 | 2 | 7.6 | 12▲785.7% | 40▲21.5% |
| G. YowWinger | New England Revolution | 🇺🇸USA | 24 | 22 | 1 | 0 | 7 | 8▼21.1%↩ | 40▼18.7%↩ |
| G. TapiaCentre-forward | Columbus Crew | 🇨🇱Chile | 24 | 6 | 1 | 1 | 7.2 | 5▼75.3%↩ | 40▼38%↩ |
| A. IbrahimCentre-forward | Houston Dynamo | 🇳🇬Nigeria | 24 | 22 | 2 | 0 | 7.3 | 10▼34.2%↩ | 40▼2.2%↩ |
| Talles MagnoWinger | New York City FC | 🇧🇷Brazil | 24 | 18 | 2 | 2 | 7.5 | 15▲5.6%↩ | 40▼31.3%↩ |
| Loïc WilliamsCentre-back | Colorado Rapids | 🇪🇸Spain | 24 | 15 | 1 | 0 | 7.4 | 16▼54.5%↩ | 40▼37.7%↩ |
| Nico CavalloCentre-back | New York City FC | 🇺🇸USA | 24 | 18 | 0 | 0 | 7.4 | 16▲178% | 39▲13% |
| T. CorbeanuWinger | Toronto FC | 🇨🇦Canada | 24 | 17 | 3 | 5 | 7.8 | 13▼55% | 39▼12.1% |
| A. AnelloAttacking midfielder | Philadelphia Union | 🇺🇸USA | 24 | 15 | 1 | 1 | 7.2 | 9▲172.7%↩ | 39▼17%↩ |
| CapitaWinger | Sporting Kansas City | 🇦🇴Angola | 24 | 17 | 2 | 1 | 7 | 17▼18.1%↩ | 39▲10.5%↩ |
| J. CaicedoDefensive midfielder | Portland Timbers | 🇨🇴Colombia | 24 | 19 | 0 | 0 | 7.4 | 17▲34.4%↩ | 39▼17.3%↩ |
| S. BangouraDefensive midfielder | Columbus Crew | 🇬🇳Guinea | 24 | 19 | 1 | 0 | 7.1 | 15▲57.1%↩ | 38▲4.9%↩ |
| A. BonetigCentre-back | Portland Timbers | 🇦🇺Australia | 24 | 8 | 1 | 0 | 6.8 | 6▼34.1%↩ | 38▲126.8%↩ |
| J. MosqueraFull-back | Portland Timbers | 🇨🇴Colombia | 24 | 3 | 1 | 1 | 6.9 | 1▼95% | 38▼10.6% |
| A. MightenWinger | San Diego | 🏴England | 24 | 13 | 0 | 2 | 6.7 | 9▲83.3% | 38▼2.8% |
| Brendan McSorleyCentre-forward | St. Louis City | 🇺🇸USA | 24 | 12 | 1 | 0 | 7.3 | 5▼32.9% | 38▲2.2% |
| A. AravenaCentral midfielder | Portland Timbers | 🇨🇱Chile | 24 | 19 | 1 | 0 | 7 | 8▼21%↩ | 37▼38.3%↩ |
| Antino LopezCentre-back | Seattle Sounders | 🇺🇸USA | 24 | 12 | 0 | 0 | 7 | 9 | 37▲8.4% |
| C. HarperWinger |  New York Red Bulls | 🇺🇸USA | 24 | 10 | 1 | 1 | 7 | 4▼71.1% | 37▼5.4% |
| I. BoehmerGoalkeeper | Vancouver Whitecaps | 🇨🇦Canada | 24 | 2 | 0 | 0 | 6.9 | 5 | 37▲6.3% |
| Malik HenryCentral midfielder | Toronto FC | 🇨🇦Canada | 24 | 16 | 0 | 0 | 7.2 | 5▲117.4% | 37▲4% |
| P. KingstonCentral midfielder | Seattle Sounders | 🏳️ | 24 | 22 | 0 | 0 | 7.1 | 9 | 37▲8.6% |
| Kenny NielsenCentre-back | Los Angeles FC | 🇺🇸USA | 24 | 6 | 0 | 0 | 6.8 | 5▲1225% | 37▲5.2% |
| K. NonoAttacking midfielder | DC United | 🇯🇵Japan | 24 | 12 | 2 | 2 | 7.6 | 4▼87%↩ | 36▼30.7%↩ |
| R. Ríos NovoGoalkeeper | Inter Miami | 🇦🇷Argentina | 24 | 6 | 0 | 0 | 6.7 | 4▼28.6% | 36▼6.5% |
| N. MićovićGoalkeeper | Los Angeles Galaxy | 🇷🇸Serbia | 25 | 7 | 0 | 0 | 6.8 | 2▲9.5% | 36▼7% |
| Ian SmithFull-back | Portland Timbers | 🇺🇸USA | 24 | 22 | 0 | 0 | 6.5 | 8▲19.4% | 36▼4.6% |
| B. HidalgoFull-back | CF Montreal | 🇺🇸USA | 24 | 4 | 0 | 0 | 6.4 | 4▼55.7%↩ | 35▼6.1%↩ |
| D. AyalaCentral midfielder | Inter Miami | 🇦🇷Argentina | 24 | 13 | 0 | 0 | 6.7 | 4▼91.1%↩ | 35▼19.6%↩ |
| Jansen MillerCentre-back | Sporting Kansas City | 🇺🇸USA | 24 | 16 | 0 | 0 | 6.7 | 4▼76.9% | 35▼13.9% |
| H. SulteGoalkeeper | Portland Timbers | 🇺🇸USA | 24 | 15 | 0 | 0 | 6.5 | 9 | 35▼4.9% |
| Tyger SmallsWinger | Charlotte | 🏴England | 24 | 15 | 0 | 0 | 6.4 | 0 | 35▲2.1% |
| I. ParkerCentre-back | FC Dallas | 🇺🇸USA | 24 | 0 | 0 | 0 | 6.4 | 0 | 34 |
| Maxwell MurrayCentre-back | New York City FC | 🇺🇸USA | 24 | 2 | 0 | 0 | 6.3 | 2 | 34 |
